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SERPINE1 protein, human
Known as:
SERPINE1
, Serine or Cysteine Proteinase Inhibitor Clade E Member 1
, Nexin
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Plasminogen activator inhibitor 1 (402 aa, ~45 kDa) is encoded by the human SERPINE1 gene. This protein plays a role in both cell adhesion and the…
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National Institutes of Health
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Related topics
Related topics
9 relations
Genes, Regulator
Plasminogen Activator Inhibitor 2
Plasminogen Activator Inhibitor-1 Measurement
Regulation of Proteolysis
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Broader (2)
Plasminogen Activator Inhibitor 1
Plasminogen Inactivators
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Evi1 is a survival factor which conveys resistance to both TGFβ- and taxol-mediated cell death via PI3K/AKT
Y. Liu
,
L. Chen
,
T. Ko
,
A. Fields
,
E. Thompson
Oncogene
2006
Corpus ID: 27099061
In hematopoietic cells the transforming potential of the ecotropic viral integration site 1 (Evi1) oncogene is thought to be…
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Highly Cited
2003
Highly Cited
2003
Tumor Tissue Concentrations of the Proteinase Inhibitors Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and Plasminogen Activator Inhibitor Type 1 (PAI-1) Are Complementary in Determining…
A. Schrohl
,
I. Christensen
,
+6 authors
M. Holten-Andersen
Molecular & Cellular Proteomics
2003
Corpus ID: 6262364
The purpose of this study was to investigate the association between tumor tissue levels of total tissue inhibitor of…
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Highly Cited
1995
Highly Cited
1995
A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death.
L. Houenou
,
P. Turner
,
L. Li
,
R. Oppenheim
,
B. Festoff
Proceedings of the National Academy of Sciences…
1995
Corpus ID: 1443379
Protease nexin I (PNI) is a member of the family of serine protease inhibitors (serpins) that have been shown to promote neurite…
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Highly Cited
1995
Highly Cited
1995
The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance?
A. Panahloo
,
C. Andrés
,
+4 authors
J. Yudkin
Circulation
1995
Corpus ID: 25144160
BACKGROUND The insertion/deletion (ID) polymorphism of the angiotensin-converting enzyme (ACE) gene has been associated with…
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Highly Cited
1991
Highly Cited
1991
Functional interaction of plasminogen activator inhibitor type 1 (PAI-1) and heparin.
Hartmut J. Ehrlich
,
J. Keijer
,
K. T. Preissner
,
R. K. Gebbink
,
Hans Pannekoek
Biochemistry
1991
Corpus ID: 29196719
Plasminogen activator inhibitor type 1 (PAI-1), the fast-acting inhibitor of tissue-type plasminogen activator (t-PA) and…
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Highly Cited
1989
Highly Cited
1989
Blood Collection in Strong Acidic Citrate Anticoagulant Used in a Study of Dietary Influence on Basal tPA Activity
M. Rånby
,
I Birgitta Sundell
,
Torbjörn K. Nilsson
Thrombosis and Haemostasis
1989
Corpus ID: 28546367
Summary Tissue plasminogen activator (tPA) activity in blood and blood plasma has been difficult to determine because it is…
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Highly Cited
1988
Highly Cited
1988
Tissue-type plasminogen activator binding to human endothelial cells. Evidence for two distinct binding sites.
Elliot S. Barnathan
,
Alice Kuo
,
H. V. D. Keyl
,
Keith R. McCrae
,
G. Larsen
,
D. Cines
Journal of Biological Chemistry
1988
Corpus ID: 12513979
Highly Cited
1986
Highly Cited
1986
Purification and characterization of a novel inhibitor of urokinase from human urine. Quantitation and preliminary characterization in plasma.
D. Stump
,
M. Thienpont
,
D. Collen
Journal of Biological Chemistry
1986
Corpus ID: 20487277
Highly Cited
1986
Highly Cited
1986
Inhibition of tumor-cell-mediated extracellular matrix destruction by a fibroblast proteinase inhibitor, protease nexin I.
B. Bergman
,
R. W. Scott
,
A. Bajpai
,
S. Watts
,
J. Baker
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 25972997
Human fibrosarcoma (HT-1080) cells, in contrast to normal fibroblasts, rapidly hydrolyze the glycoprotein, collagen, and elastin…
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Highly Cited
1984
Highly Cited
1984
Purification of human fibroblast urokinase proenzyme and analysis of its regulation by proteases and protease nexin.
D. Eaton
,
R. W. Scott
,
J. Baker
Journal of Biological Chemistry
1984
Corpus ID: 41045595
Recently we presented evidence that normal human foreskin fibroblasts (HF cells) limit the activity of secreted urokinase by…
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