Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

SERPINE1 protein, human

Known as: SERPINE1, Serine or Cysteine Proteinase Inhibitor Clade E Member 1, Nexin 
Plasminogen activator inhibitor 1 (402 aa, ~45 kDa) is encoded by the human SERPINE1 gene. This protein plays a role in both cell adhesion and the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The PDZ-domain-containing sorting nexin 27 (SNX27) promotes recycling of internalized transmembrane proteins from endosomes to… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Endocytic sorting of signalling receptors between recycling and degradative pathways is a key cellular process controlling the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Increased mineralocorticoid levels plus high salt promote vascular inflammation and cardiac tissue remodeling. Mineralocorticoid… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2005
Review
2005
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the Western world. Its incidence has also been… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Inflammation plays a pivotal role in atherosclerosis. In addition to being a risk marker for cardiovascular disease… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Review
2003
Review
2003
During normal pregnancy the hemostatic balance changes in the direction of hypercoagulability, thus decreasing bleeding… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Proteases are linked to the malignant phenotype of different solid tumors. Therefore, the expression of the matrix… Expand
  • figure III
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The hexosamine pathway has been implicated in the pathogenesis of diabetic complications. We determined first that hyperglycemia… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Smad proteins play a key role in the intracellular signalling of transforming growth factor beta (TGF beta), which elicits a… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Plasminogen activator inhibitor type 1 (PAI-1) contributes to the pathogenesis of atherothrombosis. Its plasma level is strongly… Expand
Is this relevant?