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SERPINB13 gene

Known as: SERPINB13, PROTEASE INHIBITOR 13, HURPIN 
 
National Institutes of Health

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Serpins

Papers overview

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2011
2011
SERPINB13 is a novel RUNX1 target gene.
RUNX1 is a critical transcription factor during embryogenesis and neoplastic disease. To identify novel transcriptional targets… Expand
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2010
2010
Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas.
Serpins (serine protease inhibitors) are known as a diverse family of protease inhibitors; however, various other biological… Expand
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2007
2007
Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis.
The serine protease inhibitor (serpin) hurpin (serpin B13) is a cross class-specific inhibitor of the cysteine protease Cathepsin… Expand
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2004
2004
Gene expression in actinic keratoses: pharmacological modulation by imiquimod.
BACKGROUND Actinic keratoses (AKs) are premalignant lesions that can progress into squamous cell carcinoma. Imiquimod, which… Expand
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Highly Cited
2003
Highly Cited
2003
Identification of 9 genes differentially expressed in head and neck squamous cell carcinoma.
BACKGROUND Current treatment modalities in squamous cell carcinoma of the head and neck have failed to improve survival. Advances… Expand
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2003
2003
Maspin – the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer – is strongly expressed in preneoplastic bronchial lesions
Maspin, SCCA1/2 and hurpin were identified by cDNA microarray analyses as dramatically differentially expressed transcripts in… Expand
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2003
2003
Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis.
Headpin (SERPINB13) is a novel member of the serine proteinase inhibitor (Serpin) gene family that was originally cloned from a… Expand
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2000
2000
Genomic cloning, mapping, structure and promoter analysis of HEADPIN, a serpin which is down-regulated in head and neck cancer cells.
Headpin is a novel serine proteinase inhibitor (serpin) that is down-regulated in squamous cell carcinoma of the oral cavity and… Expand
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1999
1999
Cloning and characterization of hurpin (protease inhibitor 13): A new skin-specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family.
Epidermal keratinocytes are the primary target of the midrange ultraviolet part (UVB, 280-320 nm) of terrestrial sunlight… Expand
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1999
1999
Identification and cDNA cloning of headpin, a novel differentially expressed serpin that maps to chromosome 18q.
Differential display was used to identify a novel serpin (headpin) underexpressed in squamous cell cancers of the oral cavity… Expand
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