SEL1L gene

Known as: SEL1L, IBD2, SEL1-LIKE 
This gene is involved in protein degradation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
051019972018

Papers overview

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2012
2012
Inherited ataxias are characterized by degeneration of the cerebellar structures, which results in progressive motor… (More)
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2011
2011
The mammalian HRD1-SEL1L complex provides a scaffold for endoplasmic reticulum (ER)-associated degradation (ERAD), thereby… (More)
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Highly Cited
2010
Highly Cited
2010
Sophisticated quality control mechanisms prolong retention of protein-folding intermediates in the endoplasmic reticulum (ER… (More)
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2010
2010
Stress in the endoplasmic reticulum (ER) plays an important causal role in the pathogenesis of several chronic diseases such as… (More)
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2009
Highly Cited
2009
Terminally misfolded or unassembled secretory proteins are retained in the endoplasmic reticulum (ER) and subsequently cleared by… (More)
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Highly Cited
2008
Highly Cited
2008
Terminally misfolded or unassembled proteins in the early secretory pathway are degraded by a ubiquitin- and proteasome-dependent… (More)
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Highly Cited
2008
Highly Cited
2008
Membrane and secretory proteins that fail to pass quality control in the endoplasmic reticulum are discharged into the cytosol… (More)
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Highly Cited
2006
Highly Cited
2006
Protein quality control in the endoplasmic reticulum (ER) involves recognition of misfolded proteins and dislocation from the ER… (More)
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2005
2005
The ectopic expression of the gene SEL1L in the human breast carcinoma cell line MCF-7 resulted in a reduction of the aggressive… (More)
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2005
2005
Previously, it was reported that SEL1L is able to decrease the aggressive behavior of human pancreatic tumor cells both in vitro… (More)
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