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SEL1L gene

Known as: SEL1L, IBD2, SEL1-LIKE 
This gene is involved in protein degradation.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
West Nile virus (WNV) causes an acute neurological infection attended by massive neuronal cell death. However, the mechanism(s… Expand
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2014
2014
Sel1L is an essential adaptor protein for the E3 ligase Hrd1 in the endoplasmic reticulum (ER)-associated degradation (ERAD), a… Expand
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2013
2013
Proteins misfolded in the endoplasmic reticulum (ER) are cleared by the ubiquitin-dependent proteasome system in the cytosol, a… Expand
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2012
2012
Inherited ataxias are characterized by degeneration of the cerebellar structures, which results in progressive motor… Expand
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Highly Cited
2010
Highly Cited
2010
Sophisticated quality control mechanisms prolong retention of protein-folding intermediates in the endoplasmic reticulum (ER… Expand
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Highly Cited
2009
Highly Cited
2009
Terminally misfolded or unassembled secretory proteins are retained in the endoplasmic reticulum (ER) and subsequently cleared by… Expand
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Highly Cited
2008
Highly Cited
2008
Terminally misfolded or unassembled proteins in the early secretory pathway are degraded by a ubiquitin- and proteasome-dependent… Expand
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Highly Cited
2008
Highly Cited
2008
Membrane and secretory proteins that fail to pass quality control in the endoplasmic reticulum are discharged into the cytosol… Expand
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Highly Cited
2006
Highly Cited
2006
Protein quality control in the endoplasmic reticulum (ER) involves recognition of misfolded proteins and dislocation from the ER… Expand
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Review
2006
Review
2006
Since the cloning in 1997 of SEL1L, the human ortholog of the sel-1 gene of C. elegans, most studies have focused on its role in… Expand
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