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SCH 79797

Known as: SCH-79797, SCH79797 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Role of proteinase-activated receptors 1 and 2 in nonsteroidal anti-inflammatory drug enteropathy
The use of nonsteroidal anti-inflammatory drugs (NSAIDs) can promote lower gastrointestinal detrimental effects. Proteinase… 
Review
2018
Review
2018
The PAR 1 antagonist , SCH 79797 , alters platelet morphology and function indepen-dently of PARs
doi:10.1160/TH12-06-0389 Thromb Haemost 2013; 109: 164–167 Dear Sirs, Protease-activated receptors (PARs) are a family of four G… 
2016
2016
The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation.
During asthma exacerbation, plasma circulating coagulant factor X (FX) enters the inflamed airways and is activated (FXa). FXa… 
2016
2016
Pravastatin and C reactive protein modulate protease- activated receptor-1 expression in vitro blood platelets.
Protease-activated receptor-1 (PAR-1) plays an important role in mediating activation of human platelets by thrombin. However… 
2014
2014
Antithrombotic effects of PAR1 and PAR4 antagonists evaluated under flow and static conditions.
2014
2014
[Promoting effect of thrombin on proliferation of bone marrow-derived mesenchymal stem cells and its mechanisms].
This study was aimed to investigate the growth-promoting activity of thrombin on mesenchymal stem cells (MSC) and its mechanisms… 
2012
2012
Thrombin stimulates integrin β1-dependent adhesion of human pancreatic cancer cells to vitronectin through protease-activated receptor (PAR)-1.
BACKGROUND/AIMS The aim of this study was to investigate the effect of thrombin and the thrombin receptor protease-activated… 
2011
2011
Gastrointestinal , Hepatobiliary , and Pancreatic Pathology Serine Protease Inhibition Reduces Post-Ischemic Granulocyte Recruitment in Mouse Intestine
Thomas Gobbetti,* Nicolas Cenac,* Jean-Paul Motta,* Corinne Rolland,* Laurence Martin,* Patricia Andrade-Gordon, Martin Steinhoff… 
2008
2008
Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation.
Thrombin is a potent stimulant of smooth muscle cell (SMC) proliferation in inflammatory conditions, leading to pathological… 
Highly Cited
2006
Highly Cited
2006
Blockade of Angiogenesis by Small Molecule Antagonists to Protease-Activated Receptor-1: Association with Endothelial Cell Growth Suppression and Induction of Apoptosis
Many studies support the notion that protease-activated receptor (PAR)-1 plays a pivotal role in angiogenesis. However, direct… 
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