SB 742457

Known as: SB-742457, SB742457 
 

Topic mentions per year

Topic mentions per year

2009-2018
01220092018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Modulators of the serotonin 5-HT6 receptor (5-HT6R) offer a promising strategy for the treatment of the cognitive deficits that… (More)
  • figure 2
  • figure 1
  • figure 3
  • table 1
  • table 2
Is this relevant?
2016
2016
Within the past decade several novel targets have been indicated as key players in Alzheimer-type dementia and associated… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 3
Is this relevant?
2015
2015
Whilst the FDA-approved anorectic, lorcaserin and various 5-hydroxytryptamine (5-HT)6 receptor antagonists reduce feeding, a… (More)
  • figure 2
  • figure 1
  • table 1
  • table 2
Is this relevant?
2015
2015
UNLABELLED Antagonism of 5-hydroxytrypamine-6 (5HT6) receptors is associated with procognitive effects in preclinical species… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
2013
2013
Scopolamine, a non-selective muscarinic receptor antagonist has widespread central nervous system effects. Muscarinic receptors… (More)
Is this relevant?
2012
2012
The serotonin6 (5-HT(6)) receptor has received attention for its proposed role in cognitive impairments associated with… (More)
Is this relevant?
2011
2011
OBJECTIVE To estimate the treatment effects of SB-742457 and donepezil in Alzheimer disease (AD) in a contemporary clinical trial… (More)
Is this relevant?
2011
2011
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Several lines of evidence suggest a possible role of 5-HT(6) receptor antagonists in… (More)
Is this relevant?
2010
2010
BACKGROUND This randomized, double-blind, placebo-controlled study investigated the efficacy and tolerability of the 5-HT6… (More)
Is this relevant?
2009
2009
This study examined the efficacy of sertindole in comparison with a selective 5-HT6 and a 5-HT2A receptor antagonist to reverse… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?