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SB 742457

Known as: SB-742457, SB742457 
 
National Institutes of Health

Papers overview

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2016
2016
Modulators of the serotonin 5-HT6 receptor (5-HT6R) offer a promising strategy for the treatment of the cognitive deficits that… Expand
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2015
2015
RationaleWhilst the FDA-approved anorectic, lorcaserin and various 5-hydroxytryptamine (5-HT)6 receptor antagonists reduce… Expand
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2015
2015
Background Two previous studies of SB742457, a 5-hydroxytryptamine (5-HT6) receptor antagonist, suggested the efficacy of… Expand
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2015
2015
UNLABELLED Antagonism of 5-hydroxytrypamine-6 (5HT6) receptors is associated with procognitive effects in preclinical species… Expand
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Review
2011
Review
2011
SummaryAlzheimer’s disease (AD) is a devastating neurological condition characterized by a progressive decline in cognitive… Expand
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To estimate the treatment effects of SB-742457 and donepezil in Alzheimer disease (AD) in a contemporary clinical trial… Expand
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2011
2011
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Several lines of evidence suggest a possible role of 5-HT(6) receptor antagonists in… Expand
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2010
2010
BACKGROUND This randomized, double-blind, placebo-controlled study investigated the efficacy and tolerability of the 5-HT6… Expand
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2010
2010
Background: This randomized, double-blind, placebo-controlled study investigated the efficacy and tolerability of the 5-HT6… Expand
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Highly Cited
2009
Highly Cited
2009
AimThis study examined the efficacy of sertindole in comparison with a selective 5-HT6 and a 5-HT2A receptor antagonist to… Expand
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