Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

SB 258719

Known as: SB-258719 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
&NA; The involvement of the 5‐HT7 receptor in nociception and pain, particularly chronic pain (i.e., neuropathic pain), has been… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2010
Highly Cited
2010
Background:Tramadol is an analgesic drug, and its mechanism of action is believed to be mediated by the &mgr;-opioid receptor. A… Expand
Highly Cited
2009
Highly Cited
2009
ABSTRACT This work aimed to evaluate the potential role of the 5‐HT7 receptor in nociception secondary to a sensitizing stimulus… Expand
  • table 1
  • figure 2
  • figure 1
  • figure 4
  • figure 3
Highly Cited
2005
Highly Cited
2005
The affinity of several antidepressant and antipsychotic drugs for the 5-HT7 receptor and its CNS distribution suggest potential… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
2004
2004
Recombinant 5-hydroxytryptamine 5-HT7 receptors are known to express constitutive, i.e., agonist-independent activity… Expand
Highly Cited
2004
Highly Cited
2004
Recent studies have provided evidence that activation of 5-HT1A receptors increases epileptic activity in the WAG/Rij rat model… Expand
Highly Cited
2004
Highly Cited
2004
Midbrain slices containing the dorsal and medial raphe nuclei were prepared from rat brain, loaded with [3H]serotonin ([3H]5-HT… Expand
  • figure 1
  • table I
  • figure 2
  • figure 3
  • table II
Highly Cited
2003
Highly Cited
2003
The 5-HT(7) receptor is a recent addition to the 5-HT receptor family and to date there is no clear idea as to its potential role… Expand
Highly Cited
1999
Highly Cited
1999
A number of compounds, including the selective 5‐HT7 receptor antagonist SB‐258719, were investigated for their effect on [3H]‐5… Expand
Highly Cited
1998
Highly Cited
1998
1 The functional profile of the long form of the human cloned 5‐HT7 receptor (designated h5‐HT7(a)) was investigated using a… Expand