SB 258719

Known as: SB-258719 
 

Topic mentions per year

Topic mentions per year

1998-2016
012319982016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
BACKGROUND Tramadol is an analgesic drug, and its mechanism of action is believed to be mediated by the mu-opioid receptor. A… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
The involvement of the 5-HT(7) receptor in nociception and pain, particularly chronic pain (i.e., neuropathic pain), has been… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2009
2009
This work aimed to evaluate the potential role of the 5-HT(7) receptor in nociception secondary to a sensitizing stimulus in mice… (More)
  • table 1
  • figure 2
  • figure 1
  • figure 4
  • figure 3
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The affinity of several antidepressant and antipsychotic drugs for the 5-HT7 receptor and its CNS distribution suggest potential… (More)
Is this relevant?
2004
2004
Recombinant 5-hydroxytryptamine 5-HT7 receptors are known to express constitutive, i.e., agonist-independent activity… (More)
Is this relevant?
2004
2004
Midbrain slices containing the dorsal and medial raphe nuclei were prepared from rat brain, loaded with [3H]serotonin ([3H]5-HT… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • table II
Is this relevant?
2004
2004
Recent studies have provided evidence that activation of 5-HT1A receptors increases epileptic activity in the WAG/Rij rat model… (More)
Is this relevant?
2003
2003
The 5-HT(7) receptor is a recent addition to the 5-HT receptor family and to date there is no clear idea as to its potential role… (More)
Is this relevant?
1999
1999
1. A number of compounds, including the selective 5-HT7 receptor antagonist SB-258719, were investigated for their effect on [3H… (More)
Is this relevant?
1998
1998
1. The functional profile of the long form of the human cloned 5-HT7 receptor (designated h5-HT7(a)) was investigated using a… (More)
Is this relevant?