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SB 225002

Known as: SB-225002, SB225002 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Phenylurea Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
CXCR2 Blockade Mitigates Neural Cell Injury Following Preclinical Chorioamnionitis
Minimizing central nervous system (CNS) injury from preterm birth depends upon identification of the critical pathways that… 
2017
2017
Therapeutic inhibition of CXC chemokine receptor 2 by SB225002 attenuates LPS-induced acute lung injury in mice
Introduction Sustained neutrophilic infiltration is known to contribute to organ damage, such as acute lung injury (ALI). CXC… 
2015
2015
Autocrine control of MIP-2 secretion from metastatic breast cancer cells is mediated by CXCR2: a mechanism for possible resistance to CXCR2 antagonists
Abstract CXCR2 interacts with a wide range of chemokines and CXCR2 antagonists may have therapeutic value for treatment-resistant… 
Highly Cited
2013
Highly Cited
2013
Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres.
2013
2013
SB225002 Promotes Mitotic Catastrophe in Chemo-Sensitive and -Resistant Ovarian Cancer Cells Independent of p53 Status In Vitro
Recent evidence indicates that CXCR2 signaling is crucial for cancer progression, and its antagonist SB225002 induces apoptosis… 
Highly Cited
2010
Highly Cited
2010
The effects of the selective and non‐peptide CXCR2 receptor antagonist SB225002 on acute and long‐lasting models of nociception in mice
Highly Cited
2008
Highly Cited
2008
Hepatocyte signaling through CXC chemokine receptor‐2 is detrimental to liver recovery after ischemia/reperfusion in mice
CXC chemokines and their receptor, CXC chemokine receptor‐2 (CXCR2), are important components of the hepatic inflammatory… 
2007
2007
ELR+-CXC chemokines and their receptors in early metanephric development.
Although originally identified as mediators of inflammation, it is now apparent that chemokines play a fundamental role in tissue… 
Highly Cited
2005
Highly Cited
2005
IL-8 increases transmission of HIV type 1 in cervical explant tissue.
Interleukin-8 (IL-8) is the predominant cytokine expressed in the female genital tract of women with certain infectious… 
2004
2004
Cloning and Pharmacological Characterization of CXCR1 and CXCR2 from Macaca fascicularis
Two genes with high sequence homology to human CXCR1 (hCXCR1) and CXCR2 (hCXCR2) were cloned from blood of cynomolgus monkey… 
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