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SB 225002

Known as: SB-225002, SB225002 
National Institutes of Health

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Phenylurea Compounds

Papers overview

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2018
2018
ELR+ chemokine‐mediated neutrophil recruitment is involved in 2,4,6‐trinitrochlorobenzene‐induced contact hypersensitivity
Contact dermatitis is a form of delayed‐type hypersensitivity characterized by localized thickening, papules, redness and… 
2018
2018
Abstract 2: CXCR2+ tumor cells mediate vascular mimicry driving anti-angiogenic therapy (AAT) resistance in glioblastoma (GBM)
Glioblastoma (GBM) is a hypervascular and hypoxic neoplasia of the central nervous system with an extremely high rate of… 
2015
2015
Abstract 433: Role of IL-8/CXCR2 network in the tumor microenvironment of esophageal squamous cell carcinoma
Background: IL-8, a pro-inflammatory cytokine, and its receptor, CXCR2, are expressed in various cancer cells. The IL-8/CXCR2… 
2014
2014
CXCL 7-Mediated Stimulation of Lymphangiogenic Factors VEGF-C , VEGF-D in Human Breast Cancer Cells
Increased expression of lymphangiogenesis factors VEGF-C/D and heparanase has been correlated with the invasion of cancer… 
2014
2014
The bile acid receptor FXR controls CNS autoimmunity in an IL-10-dependent fashion
2014
2014
How hydrogen peroxide and CXCL8 modulate neutrophil recruitment "in vivo"
Tese de doutoramento, Ciencias Biomedicas (Biologia Celular e Molecular), Universidade de Lisboa, Faculdade de Medicina, 2014 
2013
2013
Role of CXCR2 on the immune modulating activity of α-iso-cubebenol a natural compound isolated from the Schisandra chinensis fruit.
2010
2010
Thrombin stimulates RPE cell motility by PKC‐ζ‐ and NF‐κB‐dependent gene expression of MCP‐1 and CINC‐1/GRO chemokines
Retinal pigment epithelial cells (RPE) are the major cell type involved in the pathogenesis of proliferative vitreoretinopathy… 
2007
2007
ELR+-CXC chemokines and their receptors in early metanephric development.
Although originally identified as mediators of inflammation, it is now apparent that chemokines play a fundamental role in tissue… 
2007
2007
Pharmacological Characterization of Sch 527123 , a Potent Allosteric CXCR 1 / CXCR 2 Antagonist
In neutrophils, growth-related protein(CXCL1) and interleukin-8 (CXCL8), are potent chemoattractants (Cytokine 14:27– 36, 2001… 
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