FAQ

SB 222200

Known as: SB-222200 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2007
0120002007

Related topics

Related topics

1 relation

Broader (1)

Quinolines

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
SB 222200
Quinolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells.
Neuropeptide tachykinins (substance P, neurokinin A, and neurokinin B) are present in peripheral terminals of sensory nerve… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Blockade of NK3R signaling in the PVN decreases vasopressin and oxytocin release and c-Fos expression in the magnocellular neurons in response to hypotension.
Tachykinin neurokinin 3 receptor (NK3R) signaling has a broad role in vasopressin (VP) and oxytocin (OT) release. Hydralazine… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Tachykinin neurokinin 3 receptor signaling in cholecystokinin-elicited release of oxytocin and vasopressin.
Neurokinin 3 receptor (NK3R) signaling has an integral role in the stimulated oxytocin (OT) and vasopressin (VP) release in… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
2007
2007
Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge.
Activation of the neurokinin 3 receptor (NK3R) by a receptor agonist, hypotension, and hyperosmolarity results in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2006
2006
Agonist and hypertonic saline-induced trafficking of the NK3-receptors on vasopressin neurons within the paraventricular nucleus of the hypothalamus.
The neurokinin 3 receptor (NK3R) is colocalized with vasopressinergic neurons within the hypothalamic paraventricular nucleus… (More)
Is this relevant?
2006
2006
CALL FOR PAPERS Neurohypophyseal Hormones: From Genomics and Physiology to Disease Agonist and hypertonic saline-induced trafficking of the NK3-receptors on vasopressin neurons within the…
Haley, Gwendolen E., and Francis W. Flynn. Agonist and hypertonic saline-induced trafficking of the NK3-receptors on vasopressin… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2005
2005
Effect of a selective and potent central nervous system penetrant, neurokinin-3 receptor antagonist (SB-222200), on cisplatin-induced emesis in the ferret.
The anti-emetic activity of selective NK-1 receptor antagonism is well established. However, little is known of the possibility… (More)
Is this relevant?
2002
2002
Neurokinin B induces oedema formation in mouse lung via tachykinin receptor-independent mechanisms.
The tachykinin neurokinin B (NKB) has been implicated in the hypertension that characterises pre-eclampsia, a condition where… (More)
Is this relevant?
2000
2000
Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist.
The pharmacological and pharmacokinetic profile of SB-222200 [(S)-(-)-N-(alpha-ethylbenzyl)-3-methyl-2-phenylquinoline-4-car… (More)
  • table 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?