SAMHD1, 9.1-KB DEL
National Institutes of Health
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SAMHD1, a host dNTPase, acts as a retroviral restriction factor by degrading the pool of nucleotides available for the initial…
目的建立慢病毒介导的稳定过表达人源SAMHD1基因的结肠癌细胞株，观察SAMHD1对细胞抗1型单纯疱疹病毒（HSV-1）感染能力的影响。 方法利用pCDH-EF1-MCS-T2A-copGFP慢病毒载体新构建了pCDH-EF1-MCS-SAMHD1-T2A…
ABSTRACT Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) is a mammalian dNTP hydrolase that acts as a negative…