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S3I 201

Known as: S3I-201, S3I201 
 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
ABSTRACT During myocardial infarction, infiltrated macrophages have pivotal roles in cardiac remodeling and delayed M1 toward M2… Expand
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2016
2016
The Signal Transducer and Activator of Transcription 3 (STAT3) oncogene is a master regulator of many human cancers, and a well… Expand
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Highly Cited
2014
Highly Cited
2014
STAT3 regulates a variety of genes involved with cell proliferation, differentiation, apoptosis, angiogenesis, metastasis… Expand
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Highly Cited
2011
Highly Cited
2011
Autosomal dominant polycystic kidney disease (ADPKD) is a commonly inherited disorder mostly caused by mutations in PKD1… Expand
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Highly Cited
2010
Highly Cited
2010
Accumulation of both interstitial myofibroblasts and excessive production of extracellular matrix proteins is a common pathway… Expand
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Highly Cited
2010
Highly Cited
2010
Constitutive activation of signal transducer and activator of transcription 3 (STAT3) signaling is frequently detected in cancer… Expand
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2010
2010
Emerging evidence demonstrates the involvement of endothelin-1 (ET-1) in the pathophysiology of cardiovascular disorders… Expand
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Highly Cited
2009
Highly Cited
2009
Signal transducer and activator of transcription 3 (Stat3) protein is a cytosolic transcription factor that relays signals from… Expand
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Highly Cited
2007
Highly Cited
2007
S3I-201 (NSC 74859) is a chemical probe inhibitor of Stat3 activity, which was identified from the National Cancer Institute… Expand
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Highly Cited
2007
Highly Cited
2007
Stat3 is hyperactivated in many human tumors and represents a valid target for anticancer drug design. We present a novel small… Expand
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