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S3I 201
Known as:
S3I-201
, S3I201
Â
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
2007-2018
0
5
10
2007
2018
Related topics
Related topics
1 relation
Broader (1)
NSC 74859
Related mentions per year
Related mentions per year
2007-2018
2000
2005
2010
2015
2020
S3I 201
NSC 74859
Papers overview
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2016
2016
Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent
Daniel P. Ball
,
Andrew J. Lewis
,
D. Victoria Williams
,
Diana Resetca
,
Derek J. Wilson
,
Patrick T Gunning
Oncotarget
2016
The Signal Transducer and Activator of Transcription 3 (STAT3) oncogene is a master regulator of many human cancers, and a well…Â
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2014
2014
Effects of AG490 and S3I-201 on regulation of the JAK/STAT3 signaling pathway in relation to angiogenesis in TRAIL-resistant prostate cancer cells in vitro
Venhar Gurbuz
,
Ece Konac
,
+4 authors
Sinan Sozen
Oncology letters
2014
The aim of the present study was to analyze the molecular mechanisms involved in blocking the signaling pathway and the effects…Â
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2014
2014
Hepatic Stellate Cell Coculture Enables Sorafenib Resistance in Huh7 Cells through HGF/c-Met/Akt and Jak2/Stat3 Pathways
Weibo Chen
,
Junhua Wu
,
+5 authors
Yitao Ding
BioMed research international
2014
PURPOSE Tumor microenvironment confers drug resistance to kinase inhibitors by increasing RKT ligand levels that result in the…Â
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2014
2014
Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening
L-J. Sally Liu
,
K-H Leung
,
Dominic S Chan
,
Y-T Wang
,
D-L Ma
,
C-H Leung
Cell Death and Disease
2014
STAT3 regulates a variety of genes involved with cell proliferation, differentiation, apoptosis, angiogenesis, metastasis…Â
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2014
2014
Interleukin-17 increases the expression of Toll-like receptor 3 via the STAT3 pathway in rheumatoid arthritis fibroblast-like synoviocytes.
Seon-Yeong Lee
,
Bo Young Yoon
,
+6 authors
Mi-La Cho
Immunology
2014
We examined the effect of interleukin-17 (IL-17) on the expression of Toll-like receptors (TLRs) in fibroblast-like synoviocytes…Â
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2014
2014
Essential role of IL-10/STAT3 in chronic stress-induced immune suppression.
Dan Hu
,
Lei Wan
,
+4 authors
Deling Yin
Brain, behavior, and immunity
2014
Stress can either enhance or suppress immune functions depending on a variety of factors such as duration of stressful condition…Â
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2013
2013
STAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cells
H-Y. Lin
,
C-H Chiang
,
W-C Hung
British Journal of Cancer
2013
Background:Signal transducer and activator of transcription 3 (STAT3) activation is frequently found in human lung cancer and is…Â
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2012
2012
Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis.
Nandini Sen
,
Xibing Che
,
+4 authors
Ann. M. Arvin
Proceedings of the National Academy of Sciences…
2012
Varicella-zoster virus (VZV) is a human α-herpesvirus that causes varicella (chickenpox) during primary infection and zoster…Â
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Highly Cited
2010
Highly Cited
2010
A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy.
Maoyin Pang
,
Li Ma
,
+7 authors
Shougang Zhuang
Kidney international
2010
Accumulation of both interstitial myofibroblasts and excessive production of extracellular matrix proteins is a common pathway…Â
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Highly Cited
2007
Highly Cited
2007
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
Khandaker Al Zaid Siddiquee
,
Shumin Zhang
,
+9 authors
James Turkson
Proceedings of the National Academy of Sciences…
2007
S3I-201 (NSC 74859) is a chemical probe inhibitor of Stat3 activity, which was identified from the National Cancer Institute…Â
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