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S3I 201

Known as: S3I-201, S3I201 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2018
051020072018

Related topics

Related topics

1 relation

Broader (1)

NSC 74859

Related mentions per year

Related mentions per year

2007-2018
20002005201020152020
S3I 201
NSC 74859

Papers overview

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2016
2016
Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent
The Signal Transducer and Activator of Transcription 3 (STAT3) oncogene is a master regulator of many human cancers, and a well… (More)
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2014
2014
Effects of AG490 and S3I-201 on regulation of the JAK/STAT3 signaling pathway in relation to angiogenesis in TRAIL-resistant prostate cancer cells in vitro
The aim of the present study was to analyze the molecular mechanisms involved in blocking the signaling pathway and the effects… (More)
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2014
2014
Hepatic Stellate Cell Coculture Enables Sorafenib Resistance in Huh7 Cells through HGF/c-Met/Akt and Jak2/Stat3 Pathways
PURPOSE Tumor microenvironment confers drug resistance to kinase inhibitors by increasing RKT ligand levels that result in the… (More)
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2014
2014
Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening
STAT3 regulates a variety of genes involved with cell proliferation, differentiation, apoptosis, angiogenesis, metastasis… (More)
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2014
2014
Interleukin-17 increases the expression of Toll-like receptor 3 via the STAT3 pathway in rheumatoid arthritis fibroblast-like synoviocytes.
We examined the effect of interleukin-17 (IL-17) on the expression of Toll-like receptors (TLRs) in fibroblast-like synoviocytes… (More)
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2014
2014
Essential role of IL-10/STAT3 in chronic stress-induced immune suppression.
Stress can either enhance or suppress immune functions depending on a variety of factors such as duration of stressful condition… (More)
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2013
2013
STAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cells
Background:Signal transducer and activator of transcription 3 (STAT3) activation is frequently found in human lung cancer and is… (More)
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2012
2012
Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis.
Varicella-zoster virus (VZV) is a human α-herpesvirus that causes varicella (chickenpox) during primary infection and zoster… (More)
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Highly Cited
2010
Highly Cited
2010
A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy.
Accumulation of both interstitial myofibroblasts and excessive production of extracellular matrix proteins is a common pathway… (More)
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Highly Cited
2007
Highly Cited
2007
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
S3I-201 (NSC 74859) is a chemical probe inhibitor of Stat3 activity, which was identified from the National Cancer Institute… (More)
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