S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity

Known as: RUMT activity, M5U-methyltransferase activity, transfer RNA uracil methylase activity 
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2000
02419902000

Papers overview

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2000
2000
The TPsiC stem and loop (TSL) of tRNA contains highly conserved nucleoside modifications, m(5)C(49), T(54), Psi(55)and m(1)A(58… (More)
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1998
1998
Solution structures are typically average structures determined with the help of nmr-derived distance and torsion angle… (More)
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1997
1997
tRNA (m5U54)-methyltransferase (RUMT) catalyzes the S-adenosylmethionine-dependent methylation of uridine-54 in the T psi C-loop… (More)
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1996
1996
tRNA (m5U54)-methyltransferase (RUMT) catalyzes the methylation of U54 of tRNAs. In contrast to enzymes which recognize a… (More)
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1995
1995
The catalytic mechanism of tRNA(m5U54)-methyltransferase (RUMT) involves the formation of a covalent adduct between Cys324 of… (More)
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1994
1994
16S rRNA, isolated from Escherichia coli or synthesized in vitro, is methylated by tRNA (m5U54)-methyltransferase (RUMT) and S… (More)
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1994
1994
We report an extremely high-level expression system for tRNA (m5U54)-methyltransferase (RUMT), and a purification strategy which… (More)
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1992
1992
The interaction of tRNA (m5U54)-methyltransferase (RUMT) with in vitro synthesized unmodified tRNA and a 17-base… (More)
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1991
1991
Fragments of Escherichia coli FUra-tRNA(1Val) as small as 15 nucleotides form covalent complexes with tRNA (m5U54… (More)
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1991
1991
tRNA (m5U54)-methyltransferase (RUMT) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the 5… (More)
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