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S 32504
Known as:
S-32504
, S32504
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Oxazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Modulations of the amide function of the preferential dopamine D3 agonist (R,R)-S32504: improvements of affinity and selectivity for D3 versus D2 receptors.
J. Péglion
,
C. Poitevin
,
C. Mannoury la Cour
,
D. Dupuis
,
M. Millan
Bioorganic & Medicinal Chemistry Letters
2009
Corpus ID: 206239897
2007
2007
Discriminative stimulus properties of S32504, a novel D3/D2 receptor agonist and antiparkinson agent, in rats: attenuation by the antipsychotics, aripiprazole, bifeprunox, N-desmethylclozapine, and…
M. Millan
,
L. Iob
,
J. Péglion
,
A. Dekeyne
Psychopharmacology
2007
Corpus ID: 20395756
RationaleDrug-discrimination studies have proven instructive in the characterization of psychotropic agents, a procedure applied…
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2006
2006
Antiparkinsonian effects of the novel D3/D2 dopamine receptor agonist, S32504, in MPTP‐lesioned marmosets: Mediation by D2, not D3, dopamine receptors
M. Hill
,
P. Ravenscroft
,
+4 authors
M. Millan
Movement Disorders
2006
Corpus ID: 20595524
L‐dopa remains the most common treatment for Parkinson's disease. However, there is considerable interest in D3/D2 receptor…
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Highly Cited
2004
Highly Cited
2004
S32504, a Novel Naphtoxazine Agonist at Dopamine D3/D2 Receptors: III. Actions in Models of Potential Antidepressive and Anxiolytic Activity in Comparison with Ropinirole
M. Millan
,
M. Brocco
,
+5 authors
A. Dekeyne
Journal of Pharmacology and Experimental…
2004
Corpus ID: 11497059
In forced-swim tests in mice and rats, the novel D3/D2 receptor agonist S32504 [(+)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl-4…
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Highly Cited
2004
Highly Cited
2004
S32504, a Novel Naphtoxazine Agonist at Dopamine D3/D2 Receptors: II. Actions in Rodent, Primate, and Cellular Models of Antiparkinsonian Activity in Comparison to Ropinirole
M. Millan
,
B. di Cara
,
+10 authors
M. Brocco
Journal of Pharmacology and Experimental…
2004
Corpus ID: 11925317
These studies evaluated the potential antiparkinsonian properties of the novel dopamine D3/D2 receptor agonist S32504 [(+)-trans…
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2004
2004
S32504, a Novel Naphtoxazine Agonist at Dopamine D3/D2 Receptors: I. Cellular, Electrophysiological, and Neurochemical Profile in Comparison with Ropinirole
M. Millan
,
D. Cussac
,
+5 authors
J. Péglion
Journal of Pharmacology and Experimental…
2004
Corpus ID: 2860551
S32504 [(+)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl-4-propyl-2H-naphth[1,2-b]-1,4-oxazine] displayed marked affinity for…
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2004
2004
Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells.
Steve P. Presgraves
,
Sabine Borwege
,
M. Millan
,
J. Joyce
Experimental Neurology
2004
Corpus ID: 24671718
Anti-parkinsonian agents possessing both D(2) and D(3) receptor agonist properties are neuroprotective against 1-methyl-4…
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Highly Cited
2003
Highly Cited
2003
Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6…
J. Joyce
,
Steve P. Presgraves
,
+6 authors
M. Millan
Experimental Neurology
2003
Corpus ID: 24352728
Highly Cited
2003
Highly Cited
2003
Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole
R. Maggio
,
M. Scarselli
,
F. Novi
,
M. Millan
,
G. Corsini
Journal of Neurochemistry
2003
Corpus ID: 25609069
Recombinant, human dopamine D3 and D2 receptors form functional heterodimers upon co‐expression in COS‐7 cells. Herein, actions…
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2003
2003
Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice
A. Yarkov
,
D. Hanger
,
Maria Reploge
,
J. Joyce
Pharmacology, Biochemistry and Behavior
2003
Corpus ID: 40950789
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