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S-2251

Known as: S 2251 
 
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet
A strong fibrinolytic activity was demonstrated in the vegetable cheese Natto, which is a typical soybean food eaten in Japan… Expand
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Highly Cited
2001
Highly Cited
2001
Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and…
hK4 (prostase, KLK4), a recently cloned prostate-specific serine protease and a member of the tissue kallikrein family, is a… Expand
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1995
1995
Antifibrinolytic effect of recombinant apolipoprotein(a) in vitro is primarily due to attenuation of tPA-mediated Glu-plasminogen activation.
The effect of a 17-kringle form of recombinant apo(a) [r-apo(a)] on in vitro fibrin clot lysis was studied. In these assays… Expand
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1995
1995
Identification of an inhibitor of tissue-type plasminogen activator-mediated fibrinolysis in human neutrophils. A role for defensin.
An inhibitor of tissue-type plasminogen activator (tPA)-mediated and plasminogen-dependent fibrinolysis was isolated from human… Expand
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1995
1995
In vitro oxidative damage to tissue-type plasminogen activator: a selective modification of the biological functions.
OBJECTIVE Tissue-type plasminogen activator (t-PA) is an important component of the blood fibrinolytic system responsible for… Expand
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1990
1990
Binding and activation of plasminogen at the surface of Staphylococcus aureus. Increase in affinity after conversion to the Lys form of the ligand.
Untreated Staphylococcus aureus cells, strain Cowan I, specifically bound 125I-Glu-plasminogen. The binding was inhibited by both… Expand
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1989
1989
Plasminogen activators in human prostate cancer cell lines and tumors: correlation with the aggressive phenotype.
The levels of several tumor associated proteases, including plasminogen activators (PA), are elevated in many malignant tumors… Expand
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Highly Cited
1982
Highly Cited
1982
A simple, sensitive spectrophotometric assay for extrinsic (tissue-type) plasminogen activator applicable to measurements in plasma.
An indirect spectrophotometric assay for extrinsic plasminogen activator has been devised, which is based on the parabolic assay… Expand
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1979
1979
Plasminogen assay in rabbit, rat and mouse plasma using the chromogenic substrate s-2251.
Abstract An amidolytic assay has been developed for measuring plasminogen in rabbit, rat and mouse plasma using the synthetic… Expand
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Highly Cited
1978
Highly Cited
1978
Methods for determination of plasmin, antiplasmin and plasminogen by means of substrate S-2251.
The chromogenic substrate S-2251 (H-D-Val-Leu-Lys-pNA), a selective and sensitive substrate for plasmin activity, has made it… Expand
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