S 2238

In the present study, a thrombin-like enzyme named BpSP-I was isolated from Bothrops pauloensis snake venom and its biochemical… (More)

Activation of prothrombin by factor X(a) requires proteolysis of two bonds and is commonly assumed to occur via by two parallel… (More)

Glycyrrhizin (GL), an anti-inflammatory compound isolated from Glycyrrhiza glabra, was identified as a new thrombin inhibitor: (a… (More)

We describe a patient with severe epistaxis, prolonged coagulation tests and decreased plasma factor V following exposure to… (More)

Thrombin binds to fibrin at two classes of non-substrate sites, one of high affinity and the other of low affinity. We… (More)

The cDNA of the human endothelial cell thrombin receptor has been cloned and a chimeric fusion protein consisting of glutathione… (More)

Assays for antithrombin III activity using the chromogenic substrate S-2238 were automated in various modifications on various… (More)

Protein C is a vitamin K-dependent plasma protein. Activated protein C is a potent anticoagulant and enhances blood clot lysis… (More)

During the amino acid sequence determination of crotalase (EC 3.4.21.30), the thrombin-like enzyme from the venom of Crotalus… (More)

Synthetic substrates have recently been developed for the assay of several of the proteolytic enzymes required for blood… (More)