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S 18327

Known as: 1-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)ethyl)-3-phenylimidazolin-2-one, S-18327, S18327 
National Institutes of Health

Papers overview

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2001
2001
The use of pharmacokinetic/pharmacodynamic (PK/PD) analysis in early compound development was investigated in the rat for two… 
2000
2000
S18327 was dose-dependently active in several models of potential antipsychotic activity involving dopaminergic hyperactivity… 
2000
2000
S18327 displayed modest affinity for human (h)D(2) and hD(3) receptors and high affinity for hD(4) receptors. At each, S18327… 
2000
2000
S18327 was dose-dependently active in several models of potential antipsychotic activity involving dopaminergic hyperactivity…