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S 18327

Known as: 1-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)ethyl)-3-phenylimidazolin-2-one, S-18327, S18327 
 
National Institutes of Health

Papers overview

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2003
2003
Employing a two-lever, food-reinforced FR10 procedure, rats were trained to recognize a discriminative stimulus (DS) elicited by… Expand
2001
2001
The use of pharmacokinetic/pharmacodynamic (PK/PD) analysis in early compound development was investigated in the rat for two… Expand
2000
2000
S18327 was dose-dependently active in several models of potential antipsychotic activity involving dopaminergic hyperactivity… Expand
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2000
2000
S18327 displayed modest affinity for human (h)D(2) and hD(3) receptors and high affinity for hD(4) receptors. At each, S18327… Expand
2000
2000
S18327 was dose-dependently active in several models of potential antipsychotic activity involving dopaminergic hyperactivity… Expand