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S 16257

Known as: S-16257 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
AbstractIntroduction: Ivabradine is a heart rate-lowering agent that selectively inhibits the pacemaker current, If, in the… Expand
Highly Cited
1998
Highly Cited
1998
Ivabradine (S‐16257) is a new bradycardic agent with a direct effect on the sinus node. Its N‐dealkylated metabolite, S‐18982… Expand
1998
1998
Heart rate (HR) and heart rate variability (HRV) are risk markers in cardiac disease. HRV is also an index of the sympathovagal… Expand
Highly Cited
1996
Highly Cited
1996
1 The effect of the bradycardic agent S 16257 on the main ionic mechanisms of diastolic depolarization in sinoatrial node cells… Expand
Highly Cited
1995
Highly Cited
1995
The effects of (7,8-dimethoxy 3-[3-([(1S)-(4,5-dimethoxybenzocyclobutan-1-yl)methyl]methylamino) - propyl]1,3,4,5-tetrahydro-2H… Expand
Highly Cited
1994
Highly Cited
1994
1 S 16257 is a new bradycardic agent. Its electropharmacological profile has been compared to that of the known bradycardic… Expand