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Rocornal

Known as: UCB Brand of Trapidil 
National Institutes of Health

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Trapidil

Papers overview

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1992
1992
Pharmacokinetics of trapidil (Rocornal) in patients with chronic liver disease.
The pharmacokinetics of trapidil (Rocornal, Deutsches Hydrierwerk Rodleben GmbH) were studied in 15 patients with chronic liver… 
1991
1991
Influence of trapidil and derivatives on cholesterol synthesis and esterification in cultured cells.
1990
1990
[Biotransformation of the trapidil (rocornal) derivative AR 12463 in the rat].
After p.o. administration of 5-piperidino-7-[N-pentyl-N-(beta- hydroxyethyl)]amino-s-triazolo[1,5-a]pyrimidine (1; AR 12463) more… 
1990
1990
[Biotransformation of the trapidil (Rocornal) derivative AR 12,463 by the isolated, perfused rat liver and rat hepatocyte suspension cultures].
1984
1984
Bronchodilatory effect of trapidil in man.
Trapidil (Rocornal) is clinically used as a coronary vasodilator and inhibitor of coagulation of the platelet. Recently trapidil… 
1983
1983
[The modification of the biosynthesis and effect of thromboxane A2 and prostacyclin by trapidil (Rocornal)].
The influence of the antianginal drug trapidil on the biosynthesis of thromboxane A2 (TXA2) and/or prostacyclin (PGI2… 
1983
1983
Antianginal drug trapidil (Rocornal) inhibits spreading of platelets and formation of surface-bound thrombi-like aggregates.
1981
1981
[HPLC of trapidil (Rocornal) and metabolites (author's transl)].
Trapidil (1; Rocornal) and 10 metabolites can be separated by a gradient technique on reversed phases (RP-8 instant columns… 
1980
1980
Analysis of relaxant effects of trapidil in isolated dog coronary artery.
Effects of 7-diethylamino-5-methyl-s-triazolo [1,5-a]pyrimidine (trapidil, Rocornal) on dog coronary arteries were investigated… 
1971
1971
[Pharmacology of 6-methyl-7-diethylamino-s-triazolo-(1,5-a) pyrimidine (Trapymin, Rocornal), a new compound with vasodilative effects].
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