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Risperidone

Known as: risperdone, Risperidonum, Risperidone [Chemical/Ingredient] 
A benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin (5-HT) effects via cortical 5-HT2 receptor, and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
BACKGROUND The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents… Expand
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Highly Cited
2005
Highly Cited
2005
Risperidone and its active metabolite 9-OH-risperidone were compared to reference antipsychotic drugs (haloperidol, pipamperone… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Aripiprazole is a dopamine D2 receptor partial agonist with partial agonist activity at serotonin 5HT1A receptors and… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Atypical antipsychotic agents, which block postsynaptic dopamine and serotonin receptors, have advantages over… Expand
Highly Cited
2002
Highly Cited
2002
BACKGROUND Prevention of relapse is a major goal of maintenance treatment in patients with psychotic disorders. We performed a… Expand
Review
1999
Review
1999
Cognitive function is markedly impaired in most patients with schizophrenia. Antecedents of this impairment are evident in… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND We report the findings from the first large, double-blind, placebo-controlled study conducted to evaluate the efficacy… Expand
Highly Cited
1999
Highly Cited
1999
OBJECTIVE Dopamine D2 receptor occupancy measurements provide a valid predictor of antipsychotic response, extrapyramidal side… Expand
Highly Cited
1999
Highly Cited
1999
Objective: To compare effects of risperidone with placebo (efficacy and tolerability) and haloperidol (tolerability) for treating… Expand
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Highly Cited
1994
Highly Cited
1994
OBJECTIVE The purpose of this study was to investigate the safety and efficacy of risperidone in the treatment of schizophrenic… Expand