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The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents… Expand Risperidone and its active metabolite 9-OH-risperidone were compared to reference antipsychotic drugs (haloperidol, pipamperone… Expand BACKGROUND
Aripiprazole is a dopamine D2 receptor partial agonist with partial agonist activity at serotonin 5HT1A receptors and… Expand BACKGROUND
Atypical antipsychotic agents, which block postsynaptic dopamine and serotonin receptors, have advantages over… Expand BACKGROUND
Prevention of relapse is a major goal of maintenance treatment in patients with psychotic disorders. We performed a… Expand Cognitive function is markedly impaired in most patients with schizophrenia. Antecedents of this impairment are evident in… Expand BACKGROUND
We report the findings from the first large, double-blind, placebo-controlled study conducted to evaluate the efficacy… Expand OBJECTIVE
Dopamine D2 receptor occupancy measurements provide a valid predictor of antipsychotic response, extrapyramidal side… Expand Objective: To compare effects of risperidone with placebo (efficacy and tolerability) and haloperidol (tolerability) for treating… Expand OBJECTIVE
The purpose of this study was to investigate the safety and efficacy of risperidone in the treatment of schizophrenic… Expand