Ribosomal Protein S6 Kinase Alpha-1, human
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Nuclear factor‐κB (NF‐κB) is an inducible transcription factor that mediates immune and inflammatory responses. NF‐κB pathways… Expand IL-5 is a major therapeutic target to reduce eosinophilia. However, all of the eosinophil-activating cytokines, such as IL-5, IL… Expand ABSTRACT Integrins play crucial roles in epithelial adhesion, proliferation, wound healing and cancer. In the epidermis, the… Expand Previously, we showed that interactions between p90RSK1 (RSK1) and the subunits of type I protein kinase A (PKA) regulate the… Expand Differentiation therapy of cancer is being explored as a potential modality for treatment of myeloid leukemia, and derivatives of… Expand The 90 kDa ribosomal S6 kinases (p90RSKs) are a family of broadly expressed serine/threonine kinases with two kinase domains… Expand The diversion of most cellular energy to fuelling actomyosin during exercise comes at a cost – a ‘switch off’ of protein… Expand Mitogen‐activated protein kinase (MAPK) modules, composed of three protein kinases activated by successive phosphorylation, are… Expand Changes in environmental conditions such as the addition of growth factors or irradiation of cells in culture first affect… Expand The activity of transcription factor NFkappaB is regulated by its subcellular localization. In most cell types, NFkappaB is… Expand