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Ribonucleoprotein, U4-U6 Small Nuclear

Known as: U4 U6 Small Nuclear Ribonucleoproteins, U4-U6 Small Nuclear Ribonucleoproteins, U4-U6 snRNP 
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U4-U6 snRNP along with the U5 snRNP preassemble into a… Expand
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Spinal muscular atrophy (SMA) is a lethal neurodegenerative disease specifically affecting spinal motor neurons. SMA is caused by… Expand
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Review
2013
Review
2013
The pentraxins are an ancient family of proteins with a unique architecture found as far back in evolution as the Horseshoe crab… Expand
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Highly Cited
2011
Highly Cited
2011
The spliceosome is a dynamic macromolecular machine that assembles on pre-messenger RNA substrates and catalyses the excision of… Expand
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Highly Cited
2007
Highly Cited
2007
Although highly homologous, the spliceosomal hPrp31 and the nucleolar Nop56 and Nop58 (Nop56/58) proteins recognize different… Expand
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Highly Cited
2006
Highly Cited
2006
Spliceosomal small nuclear ribonucleoprotein particles (snRNPs) undergo specific assembly steps in Cajal bodies (CBs… Expand
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Highly Cited
2003
Highly Cited
2003
The spliceosomal small nuclear RNAs (snRNAs) are distributed throughout the nucleoplasm and concentrated in nuclear inclusions… Expand
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Highly Cited
2002
Highly Cited
2002
During each spliceosome cycle, the U6 snRNA undergoes extensive structural rearrangements, alternating between singular, U4-U6… Expand
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Highly Cited
2000
Highly Cited
2000
The box C/D snoRNAs function in directing 2'-O-methylation and/or as chaperones in the processing of ribosomal RNA. We show here… Expand
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Highly Cited
1998
Highly Cited
1998
The first protein that binds to all newly synthesized RNA polymerase III transcripts is a highly conserved phosphoprotein known… Expand
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Highly Cited
1988
Highly Cited
1988
Splicing complexes that form a rabbit beta-globin precursor mRNA (pre-mRNA) have been analyzed for their small nuclear RNA (snRNA… Expand
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