FAQ

Ribonucleoprotein, U1 Small Nuclear

Known as: Small Nuclear Ribonucleoproteins, U1, U1 Small Nuclear Ribonucleoproteins, U1 small nuclear ribonucleoprotein 
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins… (More)

Topic mentions per year

Topic mentions per year

1983-2017
05101519832017

Related topics

Related topics

12 relations
In BloodProcess of secretionSNRNP70 geneU1 snRNP location
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Ribonucleoprotein, U1 Small Nuclear
physiological aspects
agonists
chemical synthesis
U1 snRNP location
standards characteristics

Papers overview

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Highly Cited
2013
Highly Cited
2013
Promoter directionality is controlled by U1 snRNP and polyadenylation signals
Transcription of the mammalian genome is pervasive, but productive transcription outside of protein-coding genes is limited by… (More)
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2013
2013
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Deposition of insoluble protein aggregates is a hallmark of neurodegenerative diseases. The universal presence of β-amyloid and… (More)
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Highly Cited
2006
Highly Cited
2006
U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7.
Plasmacytoid dendritic cells (PDCs), which produce IFN-alpha in response to autoimmune complexes containing nuclear antigens, are… (More)
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Highly Cited
2001
Highly Cited
2001
Arrangement of RNA and proteins in the spliceosomal U1 small nuclear ribonucleoprotein particle.
In eukaryotic cells, freshly synthesized messenger RNA (pre-mRNA) contains stretches of non-coding RNA that must be excised… (More)
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2001
2001
Autoimmune response to U1 small nuclear ribonucleoprotein (U1 snRNP) associated with cytomegalovirus infection
The induction of autoantibodies to U1 small nuclear ribonucleoprotein (U1 snRNP) complexes is not well understood. We present… (More)
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Highly Cited
1997
Highly Cited
1997
Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry.
Here we report the rapid identification of the proteins of the spliceosomal U1 small nuclear ribonucleoprotein (snRNP) from the… (More)
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Highly Cited
1994
Highly Cited
1994
Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death.
The U1 small nuclear ribonucleoprotein particle is essential for splicing of precursor mRNA, an activity that depends upon both… (More)
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Highly Cited
1994
Highly Cited
1994
SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex.
We show that addition of SR proteins to in vitro splicing extracts results in a significant increase in assembly of the earliest… (More)
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Highly Cited
1990
Highly Cited
1990
Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A.
The crystal structure of the RNA binding domain of the U1 small nuclear ribonucleoprotein A, which forms part of the… (More)
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1988
1988
Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles.
Assembly of splicing precursor RNAs into ribonucleoprotein particle (RNP) complexes during incubation in in vitro splicing… (More)
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