Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

Retinoid X Receptor alpha

Known as: RXR alpha Receptor, Receptor, RXR alpha, Retinoid X Receptor alpha [Chemical/Ingredient] 
A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES.
National Institutes of Health

Related topics

Related topics

12 relations
In BloodProcess of secretionRXRA geneRXRA wt Allele
Expand

Narrower (1)

Retinoic Acid Receptor RXR-Alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Unveiling a New Essential Cis Element for the Transactivation of the CYP3A4 Gene by Xenobiotics
Pregnane X receptor (PXR) has been shown to form a heterodimer with retinoid X receptor α (RXRα) and to bind to the distal… 
  • table 1
  • figure 2
  • figure 3
  • figure 1
  • figure 4
Highly Cited
2006
Highly Cited
2006
Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260.
As the obligate heterodimer partner to class II nuclear receptors, the retinoid X receptor alpha (RXRalpha) plays a vital… 
Highly Cited
2006
Highly Cited
2006
Coordinate Transcriptional Repression of Liver Fatty Acid-binding Protein and Microsomal Triglyceride Transfer Protein Blocks Hepatic Very Low Density Lipoprotein Secretion without Hepatosteatosis*
Unlike the livers of humans and mice, and most hepatoma cells, which accumulate triglycerides when treated with microsomal… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2003
2003
Involvement of retinoid X receptor alpha in coenzyme Q metabolism.
The nuclear retinoid X receptor alpha (RXRalpha) is the heterodimer partner in several nuclear receptors, some of them regulating… 
2002
2002
Senescence-associated decline in hepatic peroxisomal enzyme activities corresponds with diminished levels of retinoid X receptor alpha, but not peroxisome proliferator-activated receptor alpha
Aging is associated with alterations in hepatic peroxisomal metabolism and susceptibility to hepatocarcinogenicity produced by… 
2001
2001
Dual DNA-binding specificity of peroxisome-proliferator-activated receptor gamma controlled by heterodimer formation with retinoid X receptor alpha.
The peroxisome-proliferator-activated receptor gamma (PPARgamma) is a member of the steroid/thyroid nuclear receptor superfamily… 
1998
1998
Gene transcription of the retinoid X receptor alpha (RXRalpha) is regulated by fatty acids and hormones in rat hepatic cells.
This work describes the molecular mechanisms of fatty acid and hormonal modulations of the retinoid X receptor alpha (RXRalpha… 
Highly Cited
1997
Highly Cited
1997
Heterodimeric interaction between retinoid X receptor alpha and orphan nuclear receptor OR1 reveals dimerization-induced activation as a novel mechanism of nuclear receptor activation
OR1 is a member of the steroid/thyroid hormone nuclear receptor superfamily which has been described to mediate transcriptional… 
Highly Cited
1995
Highly Cited
1995
Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.
We have recently characterized a cardiac model of ventricular chamber defects in retinoid X receptor alpha (RXR alpha) homozygous… 
Highly Cited
1993
Highly Cited
1993
Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding.
The three-dimensional solution structure of the DNA binding domain (DBD) of the retinoid X receptor alpha (RXR alpha) was… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE