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Retinoid X Receptor alpha

Known as: RXR alpha Receptor, Receptor, RXR alpha, Retinoid X Receptor alpha [Chemical/Ingredient] 
A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES.
National Institutes of Health

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In BloodProcess of secretionRXRA geneRXRA wt Allele

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Retinoic Acid Receptor RXR-Alpha

Papers overview

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2019
2019
Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers
Wilson disease (WD) is an autosomal recessive disease caused by mutations in ATP7B encoding a copper transporter. Consequent… 
2009
2009
Hepatocyte retinoid X receptor alpha (RXRalpha) deficiency impairs liver regeneration through multiple pathways
Many nuclear receptors have been implicated in liver regeneration. RXRα forms heterodimers with these nuclear receptors. In the… 
2007
2007
Rosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver.
2003
2003
Involvement of retinoid X receptor alpha in coenzyme Q metabolism.
The nuclear retinoid X receptor alpha (RXRalpha) is the heterodimer partner in several nuclear receptors, some of them regulating… 
2003
2003
Thiazolidinediones inhibit growth of gastrointestinal, biliary, and pancreatic adenocarcinoma cells through activation of the peroxisome proliferator-activated receptor gamma/retinoid X receptor…
Highly Cited
2002
Highly Cited
2002
Prostatic intraepithelial neoplasia in mice with conditional disruption of the retinoid X receptor alpha allele in the prostate epithelium.
Retinoids, which are important regulators of cell growth, differentiation, and apoptosis, have been used in treatment or… 
2000
2000
Peroxisome proliferator-activated receptor alpha-mediated pathways are altered in hepatocyte-specific retinoid X receptor alpha-deficient mice.
Retinoid x receptor alpha (RXRalpha) serves as an active partner of peroxisome proliferator-activated receptor (PPARalpha). In… 
1998
1998
Gene transcription of the retinoid X receptor alpha (RXRalpha) is regulated by fatty acids and hormones in rat hepatic cells.
This work describes the molecular mechanisms of fatty acid and hormonal modulations of the retinoid X receptor alpha (RXRalpha… 
1996
1996
Ligand-dependent enhancement of human antithrombin gene expression by retinoid X receptor alpha and thyroid hormone receptor beta.
We studied potential modulators of antithrombin gene expression. A putative hormone response element (HRE) was identified by… 
Highly Cited
1994
Highly Cited
1994
Retinoid X Receptor a Transactivates the Hepatitis B Virus Enhancer 1 Element by Forming a Heterodimeric Complex with the Peroxisome Proliferator-Activated Receptor
The hepatitis B virus enhancer 1 contains a retinoic acid responsive element (RARE). We have previously demonstrated that… 
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