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Retinoid X Receptor alpha
Known as:
RXR alpha Receptor
, Receptor, RXR alpha
, Retinoid X Receptor alpha [Chemical/Ingredient]
A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES.
National Institutes of Health
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Related topics
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12 relations
In Blood
Process of secretion
RXRA gene
RXRA wt Allele
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Retinoic Acid Receptor RXR-Alpha
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers
Charles E. Mordaunt
,
D. Kieffer
,
+11 authors
V. Medici
Epigenetics & Chromatin
2019
Corpus ID: 256020796
Wilson disease (WD) is an autosomal recessive disease caused by mutations in ATP7B encoding a copper transporter. Consequent…
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2009
2009
Hepatocyte retinoid X receptor alpha (RXRalpha) deficiency impairs liver regeneration through multiple pathways
Xiaoxia Yang
,
M. Guo
,
Y. Wan
2009
Corpus ID: 83230339
Many nuclear receptors have been implicated in liver regeneration. RXRα forms heterodimers with these nuclear receptors. In the…
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2007
2007
Rosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver.
R. Ghose
,
J. Mulder
,
Richard J. von Furstenberg
,
S. Thevananther
,
F. Kuipers
,
S. Karpen
Journal of Hepatology
2007
Corpus ID: 23481062
2003
2003
Involvement of retinoid X receptor alpha in coenzyme Q metabolism.
Magnus Bentinger
,
M. Turunen
,
Xiao-xue Zhang
,
Y. Wan
,
G. Dallner
Journal of Molecular Biology
2003
Corpus ID: 10274934
The nuclear retinoid X receptor alpha (RXRalpha) is the heterodimer partner in several nuclear receptors, some of them regulating…
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2003
2003
Thiazolidinediones inhibit growth of gastrointestinal, biliary, and pancreatic adenocarcinoma cells through activation of the peroxisome proliferator-activated receptor gamma/retinoid X receptor…
M. Tsujie
,
S. Nakamori
,
+7 authors
M. Monden
Experimental Cell Research
2003
Corpus ID: 2742211
Highly Cited
2002
Highly Cited
2002
Prostatic intraepithelial neoplasia in mice with conditional disruption of the retinoid X receptor alpha allele in the prostate epithelium.
Jiapeng Huang
,
W. Powell
,
+6 authors
P. Roy-burman
Cancer Research
2002
Corpus ID: 14153981
Retinoids, which are important regulators of cell growth, differentiation, and apoptosis, have been used in treatment or…
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2000
2000
Peroxisome proliferator-activated receptor alpha-mediated pathways are altered in hepatocyte-specific retinoid X receptor alpha-deficient mice.
Y. Wan
,
Y. Cai
,
+4 authors
H. Sucov
Journal of Biological Chemistry
2000
Corpus ID: 7422921
Retinoid x receptor alpha (RXRalpha) serves as an active partner of peroxisome proliferator-activated receptor (PPARalpha). In…
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1998
1998
Gene transcription of the retinoid X receptor alpha (RXRalpha) is regulated by fatty acids and hormones in rat hepatic cells.
H. H. Steineger
,
B. Arntsen
,
O. Spydevold
,
H. Sørensen
Journal of Lipid Research
1998
Corpus ID: 38603897
This work describes the molecular mechanisms of fatty acid and hormonal modulations of the retinoid X receptor alpha (RXRalpha…
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1996
1996
Ligand-dependent enhancement of human antithrombin gene expression by retinoid X receptor alpha and thyroid hormone receptor beta.
René W. L. M. Niessen
,
Farhad Rezaee
,
Pieter H. Reitsma
,
Marjolein Peters
,
Jan J. M. de Vijlder
,
A. Sturk
Biochemical Journal
1996
Corpus ID: 19062775
We studied potential modulators of antithrombin gene expression. A putative hormone response element (HRE) was identified by…
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Highly Cited
1994
Highly Cited
1994
Retinoid X Receptor a Transactivates the Hepatitis B Virus Enhancer 1 Element by Forming a Heterodimeric Complex with the Peroxisome Proliferator-Activated Receptor
B. Huan
,
M. Kosovsky
,
Aleem Siddiqui
1994
Corpus ID: 20980347
The hepatitis B virus enhancer 1 contains a retinoic acid responsive element (RARE). We have previously demonstrated that…
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