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Retinoid X Receptor alpha
Known as:
RXR alpha Receptor
, Receptor, RXR alpha
, Retinoid X Receptor alpha [Chemical/Ingredient]
A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES.
National Institutes of Health
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Related topics
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12 relations
In Blood
Process of secretion
RXRA gene
RXRA wt Allele
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Retinoic Acid Receptor RXR-Alpha
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Unveiling a New Essential Cis Element for the Transactivation of the CYP3A4 Gene by Xenobiotics
T. Toriyabe
,
K. Nagata
,
+4 authors
Y. Yamazoe
Molecular Pharmacology
2009
Corpus ID: 19688581
Pregnane X receptor (PXR) has been shown to form a heterodimer with retinoid X receptor α (RXRα) and to bind to the distal…
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Highly Cited
2006
Highly Cited
2006
Coordinate Transcriptional Repression of Liver Fatty Acid-binding Protein and Microsomal Triglyceride Transfer Protein Blocks Hepatic Very Low Density Lipoprotein Secretion without Hepatosteatosis*
N. Spann
,
Sohye Kang
,
+5 authors
Roger A. Davis
Journal of Biological Chemistry
2006
Corpus ID: 35207682
Unlike the livers of humans and mice, and most hepatoma cells, which accumulate triglycerides when treated with microsomal…
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Highly Cited
2006
Highly Cited
2006
Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260.
T. L. Zimmerman
,
S. Thevananther
,
R. Ghose
,
A. Burns
,
S. Karpen
Journal of Biological Chemistry
2006
Corpus ID: 23122302
As the obligate heterodimer partner to class II nuclear receptors, the retinoid X receptor alpha (RXRalpha) plays a vital…
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2003
2003
Involvement of retinoid X receptor alpha in coenzyme Q metabolism.
M. Bentinger
,
M. Turunen
,
Xiao-xue Zhang
,
Y. Wan
,
G. Dallner
Journal of Molecular Biology
2003
Corpus ID: 10274934
The nuclear retinoid X receptor alpha (RXRalpha) is the heterodimer partner in several nuclear receptors, some of them regulating…
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2001
2001
Dual DNA-binding specificity of peroxisome-proliferator-activated receptor gamma controlled by heterodimer formation with retinoid X receptor alpha.
M. Okuno
,
E. Arimoto
,
Y. Ikenobu
,
T. Nishihara
,
M. Imagawa
Biochemical Journal
2001
Corpus ID: 10063521
The peroxisome-proliferator-activated receptor gamma (PPARgamma) is a member of the steroid/thyroid nuclear receptor superfamily…
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2000
2000
Peroxisome proliferator-activated receptor alpha-mediated pathways are altered in hepatocyte-specific retinoid X receptor alpha-deficient mice.
Y. Wan
,
Y. Cai
,
+4 authors
H. Sucov
Journal of Biological Chemistry
2000
Corpus ID: 7422921
Retinoid x receptor alpha (RXRalpha) serves as an active partner of peroxisome proliferator-activated receptor (PPARalpha). In…
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1998
1998
Gene transcription of the retinoid X receptor alpha (RXRalpha) is regulated by fatty acids and hormones in rat hepatic cells.
H. H. Steineger
,
B. Arntsen
,
O. Spydevold
,
H. Sørensen
Journal of Lipid Research
1998
Corpus ID: 38603897
This work describes the molecular mechanisms of fatty acid and hormonal modulations of the retinoid X receptor alpha (RXRalpha…
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Highly Cited
1997
Highly Cited
1997
Heterodimeric interaction between retinoid X receptor alpha and orphan nuclear receptor OR1 reveals dimerization-induced activation as a novel mechanism of nuclear receptor activation
F. Wiebel
,
J. Gustafsson
Molecular and Cellular Biology
1997
Corpus ID: 20925923
OR1 is a member of the steroid/thyroid hormone nuclear receptor superfamily which has been described to mediate transcriptional…
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Highly Cited
1995
Highly Cited
1995
Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.
E. Dyson
,
H. Sucov
,
+5 authors
K. Chien
Proceedings of the National Academy of Sciences…
1995
Corpus ID: 12526899
We have recently characterized a cardiac model of ventricular chamber defects in retinoid X receptor alpha (RXR alpha) homozygous…
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Highly Cited
1993
Highly Cited
1993
Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding.
M. Lee
,
S. Kliewer
,
J. Provençal
,
P. Wright
,
R. Evans
Science
1993
Corpus ID: 41001862
The three-dimensional solution structure of the DNA binding domain (DBD) of the retinoid X receptor alpha (RXR alpha) was…
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