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Retinoic acid syndrome

Known as: APL Differentiation Syndrome, Differentiation Syndrome, syndrome retinoic acid 
A syndrome observed in patients with acute promyelocytic leukemia treated with all-trans retinoic acid. It is characterized by weight gain, dyspnea… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 2009, several… Expand
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Highly Cited
2018
Highly Cited
2018
Background Mutations in the gene encoding isocitrate dehydrogenase 1 (IDH1) occur in 6 to 10% of patients with acute myeloid… Expand
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Highly Cited
2017
Highly Cited
2017
Recurrent mutations in isocitrate dehydrogenase 2 (IDH2) occur in ∼12% of patients with acute myeloid leukemia (AML). Mutated… Expand
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Highly Cited
2012
Highly Cited
2012
The treatment of acute promyelocytic leukemia has improved considerably after recognition of the effectiveness of all-trans… Expand
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Highly Cited
2009
Highly Cited
2009
Differentiation syndrome (DS) can be a life-threatening complication in patients with acute promyelocytic leukemia (APL… Expand
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Highly Cited
2008
Highly Cited
2008
An understanding of the prognostic factors associated with the various forms of induction mortality in patients with acute… Expand
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Highly Cited
2000
Highly Cited
2000
We examined the incidence, clinical course, and outcome of patients with newly diagnosed acute promyelocytic leukemia (APL) who… Expand
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Review
1998
Review
1998
SummaryThe introduction of treatment with tretinoin (all-trans retinoic acid) and its combination with antineoplastic therapy has… Expand
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Highly Cited
1997
Highly Cited
1997
Differentiation therapy with all-trans retinoic acid (ATRA) has marked a major advance and become the first choice drug in the… Expand
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Highly Cited
1992
Highly Cited
1992
OBJECTIVE To describe a novel complication of therapy with all-trans retinoic acid in patients with acute promyelocytic leukemia… Expand
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