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Retinoblastoma-Like Protein p130

Known as: Retinoblastoma Like Protein 2, Retinoblastoma-Like Protein 2, p130, Retinoblastoma-Like Protein 
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds… Expand
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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RBL2 protein, human

Papers overview

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2019
2019
Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer
Growing evidence indicates that Angiomotin (Amot)-p130 and Amot-p80 have different physiological functions. We hypothesized that… Expand
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2016
2016
Reduced angiomotin p130 expression correlates with poor prognosis in lung adenocarcinoma
Aims Lung cancer is the leading cause of cancer-related deaths worldwide, and it still results in a poor prognosis despite… Expand
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2015
2015
HPV 16E7 and 48E7 proteins use different mechanisms to target p130 to overcome cell cycle block
BackgroundRetinoblastoma like protein 2 (RBL2) or p130 is a member of the pocket protein family, which is infrequently mutated in… Expand
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Highly Cited
1997
Highly Cited
1997
Human SPA-1 Gene Product Selectively Expressed in Lymphoid Tissues Is a Specific GTPase-activating Protein for Rap1 and Rap2
Mouse Spa-1 gene with a region homologous to the human rap1GAP gene is transcriptionally induced in the lymphocytes by mitogenic… Expand
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