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Retinoblastoma-Like Protein p130

Known as: Retinoblastoma Like Protein 2, Retinoblastoma-Like Protein 2, p130, Retinoblastoma-Like Protein 
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds… 
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

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RBL2 protein, human

Papers overview

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2019
2019
Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer
Growing evidence indicates that Angiomotin (Amot)-p130 and Amot-p80 have different physiological functions. We hypothesized that… 
2016
2016
HPV 16E7 and 48E7 proteins use different mechanisms to target p130 to overcome cell cycle block
Retinoblastoma like protein 2 (RBL2) or p130 is a member of the pocket protein family, which is infrequently mutated in human… 
2016
2016
Reduced angiomotin p130 expression correlates with poor prognosis in lung adenocarcinoma
Aims Lung cancer is the leading cause of cancer-related deaths worldwide, and it still results in a poor prognosis despite… 
Highly Cited
1997
Highly Cited
1997
Human SPA-1 Gene Product Selectively Expressed in Lymphoid Tissues Is a Specific GTPase-activating Protein for Rap1 and Rap2
Mouse Spa-1 gene with a region homologous to the human rap1GAP gene is transcriptionally induced in the lymphocytes by mitogenic… 
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