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Replication Protein A 70 kDa DNA-Binding Subunit

Known as: RF-A Protein 1, RP-A p70, Replication Factor A Protein 1 
Replication protein A 70 kDa DNA-binding subunit (616 aa, ~68 kDa) is encoded by the human RPA1 gene. This protein is involved in stabilizing single… 
National Institutes of Health

Related topics

Related topics

10 relations
DNA RepairDNA Repair GeneDNA ReplicationDNA-Binding Proteins

Broader (1)

Single-Stranded DNA Binding Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein
Abstract Single-stranded DNA-binding proteins (SSBs) play a key role in genome maintenance, binding and organizing single… 
2015
2015
The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus.
Canonical single-stranded DNA-binding proteins (SSBs) from the oligosaccharide/oligonucleotide-binding (OB) domain family are… 
Highly Cited
2012
Highly Cited
2012
Specificity of binding of single-stranded DNA-binding protein to its target.
Single-stranded DNA-binding proteins (SSBs) bind single-stranded DNA (ssDNA) and participate in all genetic processes involving… 
Highly Cited
2006
Highly Cited
2006
Replication Protein A Directs Loading of the DNA Damage Checkpoint Clamp to 5′-DNA Junctions*
The heterotrimeric checkpoint clamp comprises the Saccharomyces cerevisiae Rad17, Mec3, and Ddc1 subunits (Rad17/3/1, the 9-1-1… 
2006
2006
Structural and functional analysis of the baculovirus single-stranded DNA-binding protein LEF-3.
2003
2003
Enhancement of DNA, cDNA synthesis and fidelity at high temperatures by a dimeric single-stranded DNA-binding protein.
Bacterial single-stranded DNA-binding proteins (SSBs) are required for DNA replication and repair. We have over-expressed and… 
2000
2000
Equilibrium Binding of Single-stranded DNA with Herpes Simplex Virus Type I-coded Single-stranded DNA-binding Protein, ICP8*
We have carried out solution equilibrium binding studies of ICP8, the major single-stranded DNA (ssDNA)-binding protein of herpes… 
Review
1997
Review
1997
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism.
  • M. Wold
  • Annual Review of Biochemistry
  • 1997
  • Corpus ID: 19165076
Replication protein A [RPA; also known as replication factor A (RFA) and human single-stranded DNA-binding protein] is a single… 
Highly Cited
1992
Highly Cited
1992
Purification and characterization of UL9, the herpes simplex virus type 1 origin-binding protein
UL9, the origin-binding protein of herpes simplex virus type 1 (HSV-1), has been overexpressed in an insect cell overexpression… 
Highly Cited
1980
Highly Cited
1980
recA protein-catalyzed strand assimilation: stimulation by Escherichia coli single-stranded DNA-binding protein.
The single-stranded DNA-binding protein of Escherichia coli significantly alters the strand assimilation reaction catalyzed by… 
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