Renal fibrosis

Known as: FIBROSIS KIDNEY, Kidney fibrosis, fibrosis kidneys 
Renal fibrosis is the consequence of an excessive accumulation of extracellular matrix that occurs in virtually every type of chronic kidney disease… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
  • Hui Y Lan
  • International journal of biological sciences
  • 2011
TGF-β1 has been long considered as a key mediator in renal fibrosis and induces renal scarring largely by activating its… (More)
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Highly Cited
2010
Highly Cited
2010
TGF-beta/Smad3 promotes renal fibrosis, but the mechanisms that regulate profibrotic genes remain unclear. We hypothesized that… (More)
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Highly Cited
2010
Highly Cited
2010
Fibrosis is responsible for chronic progressive kidney failure, which is present in a large number of adults in the developed… (More)
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Highly Cited
2008
Highly Cited
2008
Fibroblasts are key mediators of fibrosis in the kidney and other organs, but their origin during fibrosis is still not… (More)
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Highly Cited
2003
Highly Cited
2003
Tubulointerstitial fibrosis is the final common result of a variety of progressive injuries leading to chronic renal failure… (More)
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Review
2003
Review
2003
Epithelial-to-mesenchymal transition (EMT) involving injured epithelial cells plays an important role in the progression of… (More)
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Highly Cited
2003
Highly Cited
2003
Bone morphogenic protein (BMP)-7 is a 35-kDa homodimeric protein and a member of the transforming growth factor (TGF… (More)
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Highly Cited
2002
Highly Cited
2002
Hyperuricemia is associated with hypertension and vascular disease, but whether this represents a causal relationship or an… (More)
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Review
2001
Review
2001
Angiotensin (Ang) II, the main peptide of the renin angiotensin system (RAS), is a renal growth factor, inducing hyperplasia… (More)
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Highly Cited
1998
Highly Cited
1998
Chronic renal failure may occur in etiologically diverse renal diseases and can be caused by hemodynamic, immunologic and… (More)
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