Regulation of Cholesterol Metabolism Pathway
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The gut microbiota participates in the control of energy homeostasis partly through fermentation of dietary fibers hence… Expand OBJECTIVES
Bile acid (BA) homeostasis is regulated by intestinal cellular signaling involving the farnesoid X receptor (FXR) and… Expand The development of hepatoblastoma (HBL) is associated with failure of hepatic stem cells (HSC) to differentiate into hepatocytes… Expand Even in healthy individuals, renal function gradually declines during aging. However, an observed variation in the rate of this… Expand Alcoholic liver disease (ALD) is a common cause of advanced liver disease, and considered as a major risk factor of morbidity and… Expand Inducible degrader of the low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase that mediates the ubiquitination and… Expand Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… Expand t We investigated how cholesterol feeding regulates cholesteroll 7a-hydroxylase (CYP7A1) via the nuclear receptorss farnesokl X… Expand The nuclear receptors farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR)γ exert counter-regulatory… Expand