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Regulation of Cholesterol Metabolism Pathway

Known as: FXR and LXR Regulation of Cholesterol Metabolism 
Cholesterol is essential for life but a key in the development of heart disease. Cholesterol homeostasis is achieved through regulation of… 
National Institutes of Health

Papers overview

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2020
2020
The gut microbiota participates in the control of energy homeostasis partly through fermentation of dietary fibers hence… 
2020
2020
OBJECTIVES Bile acid (BA) homeostasis is regulated by intestinal cellular signaling involving the farnesoid X receptor (FXR) and… 
2017
2017
The development of hepatoblastoma (HBL) is associated with failure of hepatic stem cells (HSC) to differentiate into hepatocytes… 
2017
2017
Even in healthy individuals, renal function gradually declines during aging. However, an observed variation in the rate of this… 
Review
2012
Review
2012
Inducible degrader of the low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase that mediates the ubiquitination and… 
Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… 
2007
2007
  • Li
  • 2007
  • Corpus ID: 55853448
t We investigated how cholesterol feeding regulates cholesteroll 7a-hydroxylase (CYP7A1) via the nuclear receptorss farnesokl X… 
Highly Cited
2005
Highly Cited
2005
The nuclear receptors farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR)γ exert counter-regulatory…