Regulation of Cholesterol Metabolism Pathway
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The development of hepatoblastoma (HBL) is associated with failure of hepatic stem cells (HSC) to differentiate into hepatocytes… (More)
Inducible degrader of the low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase that mediates the ubiquitination and… (More)
- Journal of lipid research
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… (More)
The nuclear receptors farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR)gamma exert counter… (More)
Background/Aims: The bile salt-activated farnesoid X receptor (FXR; NR1H4) controls expression of several genes considered… (More)