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Regulation of Cholesterol Metabolism Pathway

Known as: FXR and LXR Regulation of Cholesterol Metabolism 
Cholesterol is essential for life but a key in the development of heart disease. Cholesterol homeostasis is achieved through regulation of… Expand
National Institutes of Health

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2020
2020
OBJECTIVES Bile acid (BA) homeostasis is regulated by intestinal cellular signaling involving the farnesoid X receptor (FXR) and… Expand
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2020
2020
The gut microbiota participates in the control of energy homeostasis partly through fermentation of dietary fibers hence… Expand
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2017
2017
The development of hepatoblastoma (HBL) is associated with failure of hepatic stem cells (HSC) to differentiate into hepatocytes… Expand
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2017
2017
Even in healthy individuals, renal function gradually declines during aging. However, an observed variation in the rate of this… Expand
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2014
2014
Alcoholic liver disease (ALD) is a common cause of advanced liver disease, and considered as a major risk factor of morbidity and… Expand
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Review
2012
Review
2012
Inducible degrader of the low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase that mediates the ubiquitination and… Expand
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Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… Expand
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2007
2007
  • Li
  • 2007
  • Corpus ID: 55853448
t We investigated how cholesterol feeding regulates cholesteroll 7a-hydroxylase (CYP7A1) via the nuclear receptorss farnesokl X… Expand
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Highly Cited
2005
Highly Cited
2005
The nuclear receptors farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR)γ exert counter-regulatory… Expand
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