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Regulation of Cholesterol Metabolism Pathway

Known as: FXR and LXR Regulation of Cholesterol Metabolism 
Cholesterol is essential for life but a key in the development of heart disease. Cholesterol homeostasis is achieved through regulation of… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The gut microbiota participates in the control of energy homeostasis partly through fermentation of dietary fibers hence… Expand
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2020
2020
OBJECTIVES Bile acid (BA) homeostasis is regulated by intestinal cellular signaling involving the farnesoid X receptor (FXR) and… Expand
2017
2017
The development of hepatoblastoma (HBL) is associated with failure of hepatic stem cells (HSC) to differentiate into hepatocytes… Expand
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2017
2017
Even in healthy individuals, renal function gradually declines during aging. However, an observed variation in the rate of this… Expand
Highly Cited
2014
Highly Cited
2014
Alcoholic liver disease (ALD) is a common cause of advanced liver disease, and considered as a major risk factor of morbidity and… Expand
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Review
2012
Review
2012
Inducible degrader of the low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase that mediates the ubiquitination and… Expand
Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… Expand
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2007
2007
  • Li
  • 2007
  • Corpus ID: 55853448
t We investigated how cholesterol feeding regulates cholesteroll 7a-hydroxylase (CYP7A1) via the nuclear receptorss farnesokl X… Expand
Highly Cited
2005
Highly Cited
2005
The nuclear receptors farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR)γ exert counter-regulatory… Expand
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