Refractory Mantle Cell Lymphoma

Known as: Mantle Cell Lymphoma Refractory 
Mantle cell lymphoma resistant to treatment.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Idelalisib, an oral inhibitor of phosphatidylinositol-3-kinase δ (PI3Kδ), was evaluated in a 48-week phase 1 study (50-350 mg… (More)
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2012
2012
BACKGROUND Despite therapeutic approach that combines rituximab-containing chemotherapy, followed or not by autologous stem cell… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Temsirolimus is a mammalian target of rapamycin (mTOR) inhibitor with single-agent antitumour activity in patients… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Temsirolimus, a specific inhibitor of the mammalian target of rapamycin kinase, has shown clinical activity in mantle… (More)
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Highly Cited
2009
Highly Cited
2009
Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin lymphoma with a poor prognosis following first relapse. We present a… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND We previously reported results of the phase 2, multicenter PINNACLE study, which confirmed the substantial single… (More)
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Highly Cited
2008
Highly Cited
2008
Relapse of malignancy after allogeneic hematopoietic cell transplantation (allo-HCT) remains a therapeutic challenge. Blockade of… (More)
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Highly Cited
2004
Highly Cited
2004
We carried out HLA-matched related (n = 16) and unrelated (n = 17) hematopoietic cell transplantation (HCT) in 33 patients with… (More)
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Highly Cited
2002
Highly Cited
2002
Relapsed mantle cell lymphoma is a radiation-sensitive malignancy that is unlikely to be cured by treatment with conventional… (More)
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2002
2002
The cell cycle regulatory protein cyclin D1, which is over-expressed in 95-100% of mantle cell lymphomas (MCL), is a potential… (More)
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