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Redirected Cytolysis

Known as: Redirected Cytotoxicity 
The killing of target cells by changing the natural specificity of cytotoxic T cells by the use of an antibody or other molecule capable of binding… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine‐based switch motifs
CS1 (CRACC, novel Ly9) is a novel member of the CD2 family expressed on natural killer (NK), T and stimulated B cells. Although… 
2001
2001
Human anti‐idiotypic antibodies can be good immunogens as they target FC receptors on antigen‐presenting cells allowing efficient stimulation of both helper and cytotoxic T‐cell responses
Anti‐idiotypic antibodies that mimic tumour‐associated antigens can stimulate anti‐tumour T‐cell responses. In this article, we… 
2001
2001
Rapid induction of CD95 ligand and CD4+ T cell‐mediated apoptosis by CD137 (4–1BB) costimulation
We investigated the cytolytic mechanism by CD4+ T cells in anti‐CD3 mAb‐induced redirected cytotoxicity against a murine Fc… 
Highly Cited
1996
Highly Cited
1996
Preparation of monoclonal anti‐porcine CD3 antibodies and preliminary characterization of porcine T lymphocytes
The CD3–T‐cell receptor complex is the clonotypic surface structure by which T lymphocytes recognize foreign antigens and are… 
1995
1995
Cytotoxic activity of T cells expressing different T-cell receptor variable gene products in the intestinal mucosa.
T cells recognize foreign antigen via the heterodimeric T-cell receptor (TCR).1,2 The peripheral TCR repertoire is shaped via… 
Review
1994
Review
1994
Production and use of anti-FcR bispecific antibodies.
Bispecific antibodies (BsAb) are antibodies with two different specificities. BsAb composed of anti-Fc gamma R Ab linked to anti… 
1993
1993
Coexpression of Fcγ receptor IIIA and interleukin-2 receptor β chain by a subset of human CD3+/CD8+/CD11b+ lymphocytes
In this study we identify and characterize a subset of human peripheral blood T cells, present in all individuals, that has… 
1993
1993
Coexpression of Fc gamma receptor IIIA and interleukin-2 receptor beta chain by a subset of human CD3+/CD8+/CD11b+ lymphocytes.
In this study we identify and characterize a subset of human peripheral blood T cells, present in all individuals, that has… 
1993
1993
Coexpression of Fc / Receptor (3 Chain by CD3 +/CD8 +/CD 1 lb + Receptor IIIA and Interleukin-2 a Subset of Human Lymphocytes
In this study we identify and characterize a subset of human peripheral blood T cells, present in all individuals, that has… 
1989
1989
Inhibition of cytotoxic T cell lysis by anti-CD8 monoclonal antibodies: studies with CD3-targeted cytolysis of nominal antigen-negative targets.
The function of the CD8 molecule in lympholysis mediated by cytotoxic T cells was investigated by examining possible… 
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