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Recombinant TNF-Related Apoptosis-Inducing Ligand

Known as: Dulanermin, APO2L/TRAIL, rTRAIL 
A recombinant human soluble protein corresponding to amino acids 114-281 of the Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in cancer cells while sparing normal tissues… Expand
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Review
2012
Review
2012
Increased consumption of fruit and vegetables can represent an easy strategy to significantly reduce the incidence of cancer. We… Expand
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Highly Cited
2011
Highly Cited
2011
PURPOSE To evaluate the efficacy and safety of dulanermin combined with paclitaxel and carboplatin (PC) and bevacizumab (PCB) as… Expand
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2010
2010
Purpose: In vitro sensitivity to the proapoptotic receptor agonists dulanermin (rhApo2L/TRAIL) and drozitumab (DR5-agonist… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE To determine the safety, pharmacokinetics (PK), and maximum-tolerated dose (MTD) up to a prespecified target dose of… Expand
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2009
2009
Recent studies show that apoptosis, programmed cell death, plays an important role in the normal development of the human… Expand
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2004
2004
We examined the role of osteoprotegerin (OPG) on tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced… Expand
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Highly Cited
2001
Highly Cited
2001
TNF-related apoptosis-inducing ligand (TRAIL, also called Apo2L), a novel member of TNF superfamily, induces apoptosis in… Expand
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Highly Cited
1999
Highly Cited
1999
Mechanisms accounting for protection of the fetal semiallograft from maternal immune cells remain incompletely understood. In… Expand
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Highly Cited
1998
Highly Cited
1998
TRAIL (APO-2 ligand) and CD95L (CD95/APO-1/Fas ligand) share the highest homology among the TNF family members and the ability to… Expand
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