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Recombinant Somatostatin

Known as: GH-RIH, Growth Hormone Inhibiting Hormone 
A recombinant peptide chemically identical or similar to endogenous somatostatin. Somatostatin is a cyclic tetradecapeptide regulating many endocrine… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Growth Hormone Inhibiting Hormone MeasurementSST geneSomatostatinSomatostatin Assay

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Functional Activity of the Multiligand Analog SOM230 at Human Recombinant Somatostatin Receptor Subtypes Supports Its Usefulness in Neuroendocrine Tumors
Functional gastroenteropancreatic tumors express all 5 somatostatin receptor subtypes (sst) in different quantities. Octreotide… Expand
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1999
1999
Characterisation of human recombinant somatostatin receptors. 4. Modulation of phospholipase C activity
Abstract. Total [3H]phosphoinositide (IPx) accumulation, a measure of phospholipase C (PLC) activity, induced by somatostatin… Expand
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1999
1999
Characterisation of human recombinant somatostatin receptors. 2. Modulation of GTPγS binding
Abstract. G protein activation by somatostatin (somatotropin release inhibiting factor, SRIF), cortistatin (CST) and analogues of… Expand
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Highly Cited
1999
Highly Cited
1999
Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies
Abstract. Human somatostatin receptor subtypes 1–5 (sst1–5) were characterised using the agonist radioligands [125I]LTT-SRIF28… Expand
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Highly Cited
1998
Highly Cited
1998
[125I]Tyr10-cortistatin14 labels all five somatostatin receptors
The recently cloned rat preprocortistatin, which shows homology to the preprosomatostatin peptide, is thought to be enzymatically… Expand
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1997
1997
Characterization of human recombinant somatostatin sst5 receptors mediating activation of phosphoinositide metabolism
We have functionally characterized the human recombinant somatostatin (SRIF) sst5 receptor in Chinese hamster ovary‐K1 (CHOsst5… Expand
Highly Cited
1976
Highly Cited
1976
Effect of growth hormone release-inhibiting hormone on gastric secretion, mucosal blood flow, and serum gastrin.
In dogs with gastric fistulae and Heidenhain pouches (HP) growth hormone release-inhibiting hormone (GH-RIH) infused… Expand
Highly Cited
1976
Highly Cited
1976
Effect of growth hormone-release inhibiting hormone on hormones stimulating exocrine pancreatic secretion.
The nature and extent of growth hormone-release inhibiting hormone (GH-RIH, somatostatin)-induced inhibition of pancreatic… Expand
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Highly Cited
1975
Highly Cited
1975
Radioimmunoassay for GH-Release Inhibiting Hormone 1
Summary The synthetic growth hormone release inhibiting hormone (GH-RIH) was conjugated with human serum globulin using… Expand
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Highly Cited
1974
Highly Cited
1974
Long-term Infusion of Growth Hormone Release Inhibiting Hormone in Acromegaly: Effects on Pituitary and Pancreatic Hormones
Growth hormone release inhibiting hormone (GH-RIH) was infused at a rate of 1·3 μg/min for 28 hours into four patients with… Expand
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