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Recombinant Somatostatin
Known as:
GH-RIH
, Growth Hormone Inhibiting Hormone
A recombinant peptide chemically identical or similar to endogenous somatostatin. Somatostatin is a cyclic tetradecapeptide regulating many endocrine…
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National Institutes of Health
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Related topics
Related topics
4 relations
Growth Hormone Inhibiting Hormone Measurement
SST gene
Somatostatin
Somatostatin Assay
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Functional Activity of the Multiligand Analog SOM230 at Human Recombinant Somatostatin Receptor Subtypes Supports Its Usefulness in Neuroendocrine Tumors
H. Schmid
,
P. Schoeffter
Neuroendocrinology
2004
Corpus ID: 21550450
Functional gastroenteropancreatic tumors express all 5 somatostatin receptor subtypes (sst) in different quantities. Octreotide…
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Highly Cited
1999
Highly Cited
1999
Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies
S. Siehler
,
K. Seuwen
,
D. Hoyer
Naunyn-Schmiedeberg's Archives of Pharmacology
1999
Corpus ID: 672474
Abstract. Human somatostatin receptor subtypes 1–5 (sst1–5) were characterised using the agonist radioligands [125I]LTT-SRIF28…
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1999
1999
Characterisation of human recombinant somatostatin receptors. 4. Modulation of phospholipase C activity
S. Siehler
,
D. Hoyer
Naunyn-Schmiedeberg's Archives of Pharmacology
1999
Corpus ID: 35727929
Abstract. Total [3H]phosphoinositide (IPx) accumulation, a measure of phospholipase C (PLC) activity, induced by somatostatin…
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Highly Cited
1998
Highly Cited
1998
[125I]Tyr10-cortistatin14 labels all five somatostatin receptors
S. Siehler
,
K. Seuwen
,
D. Hoyer
Naunyn-Schmiedeberg's Archives of Pharmacology
1998
Corpus ID: 13005326
The recently cloned rat preprocortistatin, which shows homology to the preprosomatostatin peptide, is thought to be enzymatically…
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1997
1997
Characterization of human recombinant somatostatin sst5 receptors mediating activation of phosphoinositide metabolism
G. Wilkinson
,
W. Feniuk
,
P. Humphrey
British Journal of Pharmacology
1997
Corpus ID: 21131089
We have functionally characterized the human recombinant somatostatin (SRIF) sst5 receptor in Chinese hamster ovary‐K1 (CHOsst5…
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1978
1978
Inhibition by somatostatin (growth-hormone release-inhibiting hormone, GH-RIH) of gastric acid and pepsin and G-cell release of gastrin.
A. Barros D'Sa
,
S. Bloom
,
J. H. Baron
Gut
1978
Corpus ID: 36172155
Somatostatin (cyclic growth-hormone release-inhibiting hormone--GH-RIH) was infused into dogs with gastric fistulae. Somatostatin…
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Highly Cited
1976
Highly Cited
1976
Effect of growth hormone release-inhibiting hormone on gastric secretion, mucosal blood flow, and serum gastrin.
S. Konturek
,
J. Tasler
,
M. Cieszkowski
,
D. Coy
,
A. Schally
Gastroenterology
1976
Corpus ID: 22150092
Highly Cited
1976
Highly Cited
1976
Effect of growth hormone-release inhibiting hormone on hormones stimulating exocrine pancreatic secretion.
S. Konturek
,
J. Tasler
,
W. Obtułowicz
,
D. Coy
,
A. Schally
Journal of Clinical Investigation
1976
Corpus ID: 995324
The nature and extent of growth hormone-release inhibiting hormone (GH-RIH, somatostatin)-induced inhibition of pancreatic…
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Highly Cited
1975
Highly Cited
1975
Radioimmunoassay for GH-Release Inhibiting Hormone 1
A. Arimura
,
H. Sato
,
D. Coy
,
A. Schally
Proceedings of the Society for Experimental…
1975
Corpus ID: 21903376
Summary The synthetic growth hormone release inhibiting hormone (GH-RIH) was conjugated with human serum globulin using…
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Highly Cited
1974
Highly Cited
1974
Long-term Infusion of Growth Hormone Release Inhibiting Hormone in Acromegaly: Effects on Pituitary and Pancreatic Hormones
G. Besser
,
C. Mortimer
,
+9 authors
A. Schally
British medical journal
1974
Corpus ID: 40176659
Growth hormone release inhibiting hormone (GH-RIH) was infused at a rate of 1·3 μg/min for 28 hours into four patients with…
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