Recombinant Pleiotrophin

Known as: HBGF-8, OSF-1, Heparin-Binding Neurotrophic Factor 
A recombinant form of the heparin-binding cytokine pleiotrophin. Developmentally regulated, pleiotrophin functions as a growth factor during… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
0519902018

Papers overview

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Highly Cited
2007
Highly Cited
2007
Matrix metalloproteinases (MMPs) exert both pro- and antiangiogenic functions by the release of cytokines or proteolytically… (More)
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Highly Cited
2005
Highly Cited
2005
It is becoming increasingly recognized that hydrogen peroxide (HP) plays a role in cell proliferation and migration. In the… (More)
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Highly Cited
2001
Highly Cited
2001
Pleiotrophin (PTN) is a secreted growth factor that induces neurite outgrowth and is mitogenic for fibroblasts, epithelial, and… (More)
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Highly Cited
1999
Highly Cited
1999
Midkine is a 13-kDa heparin-binding growth factor with 45% sequence identity to pleiotrophin. Pleiotrophin has been demonstrated… (More)
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Highly Cited
1998
Highly Cited
1998
Pleiotrophin/heparin-binding growth-associated molecule (HB-GAM) is a specific ligand of protein tyrosine phosphatase zeta… (More)
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1998
1998
Heparin-binding growth factors have been implicated in central nervous system development, regeneration and pathology. To assess… (More)
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Highly Cited
1996
Highly Cited
1996
A major chondroitin sulfate proteoglycan in the brain, 6B4 proteoglycan/phosphacan, corresponds to the extracellular region of a… (More)
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Highly Cited
1995
Highly Cited
1995
Midkine (MK) and heparin binding-growth associated molecule (HB-GAM or pleiotrophin), constitute a new family of heparin-binding… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Some growth factors may promote tumor growth by affecting tumor angiogenesis. The angiogenic growth factor… (More)
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Highly Cited
1990
Highly Cited
1990
A heparin binding mitogenic protein isolated from bovine uterus shares NH2-terminal amino acid sequence with a protein isolated… (More)
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