Recombinant Interleukin-6

Known as: B-Cell Stimulatory Factor-2, interleukin 6, HPGF 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-6 (IL-6) with antiapoptotic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
It is not clear how contracting skeletal muscles mediate the numerous and diverse metabolic and physiological effects that are… (More)
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Highly Cited
2005
Highly Cited
2005
Obesity and insulin resistance are considered chronic inflammatory states, in part because circulating IL-6 is elevated… (More)
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Highly Cited
2003
Highly Cited
2003
The purpose of the present study was to test the hypothesis that a transient increase in plasma IL-6 induces an anti-inflammatory… (More)
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Review
2002
Review
2002
The blood-brain barrier (BBB) is formed by brain endothelial cells lining the cerebral microvasculature, and is an important… (More)
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Highly Cited
1999
Highly Cited
1999
Acute-phase proteins, which respond to systemic proinflammatory cytokines such as interleuken-6, are elevated in cardiovascular… (More)
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Highly Cited
1997
Highly Cited
1997
Interleukin (IL)-6 and IL-8 are important regulators of inflammatory responses in myocardial infarction. Induction of monocyte… (More)
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Highly Cited
1996
Highly Cited
1996
Interleukin 6 (IL-6) is considered an important mediator of acute inflammatory responses. Moreover, IL-6 functions as a… (More)
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Highly Cited
1994
Highly Cited
1994
We recently demonstrated that sc administered interleukin-6 (IL-6) strongly stimulates the human hypothalamic-pituitary-adrenal… (More)
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Highly Cited
1990
Highly Cited
1990
Human hepatocytes in primary culture were used as a model system to investigate the mechanism(s) involved in the induction of the… (More)
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Highly Cited
1990
Highly Cited
1990
To date, testing of various cytokines for the stimulation of blood cell production has not demonstrated a consistent effect on… (More)
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