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Recombinant Interleukin-2

Known as: T-Cell Growth Factor, TSF, IL-2 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-2 is made by a type of T… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Although tumor-infiltrating T cells have been documented in ovarian carcinoma, a clear association with clinical… Expand
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Highly Cited
2000
Highly Cited
2000
Severe combined immunodeficiency-X1 (SCID-X1) is an X-linked inherited disorder characterized by an early block in T and natural… Expand
Highly Cited
2000
Highly Cited
2000
PURPOSE To update response duration and survival data for patients with metastatic melanoma receiving the high-dose IV bolus… Expand
Highly Cited
1998
Highly Cited
1998
Background Recombinant human interleukin-2 (aldesleukin) and recombinant human interferon alfa can induce notable tumor… Expand
Highly Cited
1995
Highly Cited
1995
PURPOSE To determine the efficacy and toxicity of a high-dose interleukin-2 (IL-2) regimen in patients with metastatic renal cell… Expand
Highly Cited
1988
Highly Cited
1988
Lymphocytes extracted from freshly resected melanomas can be expanded in vitro and can often mediate specific lysis of autologous… Expand
Highly Cited
1987
Highly Cited
1987
We studied the effects of adoptive immunotherapy with lymphokine-activated killer (LAK) cells plus interleukin-2 or therapy with… Expand
Highly Cited
1987
Highly Cited
1987
Adoptive immunotherapy involving bolus-dose recombinant interleukin-2 (rIL-2) has been reported to induce tumor regression in… Expand
Highly Cited
1985
Highly Cited
1985
We describe here the preliminary results of the systemic administration of autologous lymphokine-activated killer (LAK) cells and… Expand
Highly Cited
1984
Highly Cited
1984
The activation of human peripheral blood leukocytes or murine splenocytes with interleukin-2 (IL-2) generated cells that were… Expand