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Recombinant Interleukin-12

Known as: Natural Killer Cell Stimulatory Factor, Recombinant human interleukin-12 (IL-12) cytokine, Interleukin-12 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-12 is made mainly by B lymphocytes… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
T follicular helper (Tfh) cells help development of antibody responses via interleukin-21 (IL-21). Here we show that activated… Expand
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Highly Cited
2008
Highly Cited
2008
PURPOSE Gene-based immunotherapy for cancer is limited by the lack of safe, efficient, reproducible, and titratable delivery… Expand
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Review
2006
Review
2006
Stimulation of naïve CD8+ T cells with antigen and costimulation results in proliferation and weak clonal expansion, but the… Expand
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Highly Cited
2005
Highly Cited
2005
Mammalian Toll-like receptors (TLRs) play an important role in the innate recognition of pathogens by dendritic cells (DCs… Expand
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Review
2005
Review
2005
Understanding the factors that influence T helper 1 (TH1)- and TH2-cell responses has been one of the main focuses of immunology… Expand
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Highly Cited
2004
Highly Cited
2004
Natural interferon-producing cells (IPC) respond to viruses by secreting type I interferon (IFN) and interleukin-12 (IL-12). Toll… Expand
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Highly Cited
2003
Highly Cited
2003
Interleukin-12 (IL-12) is a heterodimeric molecule composed of p35 and p40 subunits. Analyses in vitro have defined IL-12 as an… Expand
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Review
2003
Review
2003
The inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, are chronic inflammatory disorders of the… Expand
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Highly Cited
2002
Highly Cited
2002
Human heat-shock protein (HSP)70 activates innate immune cells and hence requires no additional adjuvants to render bound… Expand
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Highly Cited
1997
Highly Cited
1997
Immunity to Mycobacterium tuberculosis infection is associated with the emergence of protective CD4 T cells that secrete… Expand
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