Recombinant Interleukin-12

Known as: Natural Killer Cell Stimulatory Factor, Recombinant human interleukin-12 (IL-12) cytokine, Interleukin-12 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-12 is made mainly by B lymphocytes… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
05010015019922018

Papers overview

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Highly Cited
2010
Highly Cited
2010
T-cell-based immunotherapies can be effective in the treatment of large vascularized tumors, but they rely on adoptive transfer… (More)
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Highly Cited
2009
Highly Cited
2009
Differentiation of naive T lymphocytes into type I T helper (Th1) cells requires interferon-gamma and interleukin-12. It is… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Gene-based immunotherapy for cancer is limited by the lack of safe, efficient, reproducible, and titratable delivery… (More)
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Highly Cited
2004
Highly Cited
2004
Natural interferon-producing cells (IPC) respond to viruses by secreting type I interferon (IFN) and interleukin-12 (IL-12). Toll… (More)
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Highly Cited
2002
Highly Cited
2002
Interleukin-12 (IL-12) is a heterodimeric cytokine with potent immunostimulatory activity and anti-angiogenic properties. Its… (More)
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Highly Cited
1998
Highly Cited
1998
To analyze the roles of interleukin-12 (IL-12) and the IL-12-dependent Th1 response in resistance to Cryptococcus neoformans, we… (More)
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Highly Cited
1998
Highly Cited
1998
Unmethylated CpG motifs in bacterial DNA, plasmid DNA and synthetic oligodeoxynucleotides (CpG ODN) activate dendritic cells (DC… (More)
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Highly Cited
1997
Highly Cited
1997
A lymphocyte subpopulation, the Valpha14 natural killer T (NKT) cells, expresses both NK1.1 and a single invariant T cell… (More)
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Highly Cited
1996
Highly Cited
1996
Recombinant adenoviral mediated delivery of suicide and cytokine genes has been investigated as a treatment for hepatic… (More)
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Highly Cited
1996
Highly Cited
1996
The airway inflammation observed in allergic asthma is thought to be orchestrated by an antigen-driven T-helper-2 (Th2… (More)
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