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Recombinant Flt3 Ligand

Known as: Flt3-Ligand, FLT 3 Ligand, rhuFlt3L 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine Flt3. Flt3 ligand binds to the Flt3 tyrosine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Large numbers of melanoma lesions develop resistance to targeted inhibition of mutant BRAF or fail to respond to checkpoint… Expand
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Highly Cited
2008
Highly Cited
2008
The development of distinct dendritic cell (DC) subsets is regulated by cytokines. The ligand for the FMS-like tyrosine kinase 3… Expand
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Highly Cited
2006
Highly Cited
2006
Plasmacytoid dendritic cells (PDCs), which produce IFN-alpha in response to autoimmune complexes containing nuclear antigens, are… Expand
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Highly Cited
2005
Highly Cited
2005
In spite of preclinical efficacy and recent randomized, controlled studies with adenoviral vectors expressing herpes simplex… Expand
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Highly Cited
2003
Highly Cited
2003
The signals that control decisions of progenitor commitment involve the interplay of both cytokines and transcription factors… Expand
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Highly Cited
2003
Highly Cited
2003
We provide phenotypic and functional evidence of premonocytoid dendritic cells (DCs) and preplasmacytoid DCs in blood and of… Expand
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Highly Cited
2000
Highly Cited
2000
Both granulocyte-macrophage colony-stimulating factor (GM-CSF) and flt3-ligand (FL) induce the development of dendritic cells… Expand
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Highly Cited
1997
Highly Cited
1997
Daily treatment of mice with recombinant human Flt3 ligand (huFlt3L) results in a dramatic numerical increase in the number of… Expand
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Highly Cited
1996
Highly Cited
1996
B cell development is influenced by interactions between B cell progenitors and stromal cells. The precise mechanisms by which… Expand
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Highly Cited
1996
Highly Cited
1996
Flt3 ligand (flt3L) is a member of a small family of cytokines acting as tyrosine kinase receptor ligands that stimulate the… Expand
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