Recombinant Flt3 Ligand

Known as: Flt3-Ligand, FLT 3 Ligand, rhuFlt3L 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine Flt3. Flt3 ligand binds to the Flt3 tyrosine… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Plasmacytoid dendritic cells (PDCs), which produce IFN-alpha in response to autoimmune complexes containing nuclear antigens, are… (More)
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2005
2005
Ly49Q is a member of the Ly49 family that is expressed on Gr-1+ cells but not on NK and NKT cells. Ly49Q appears to be involved… (More)
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Highly Cited
2003
Highly Cited
2003
The signals that control decisions of progenitor commitment involve the interplay of both cytokines and transcription factors… (More)
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Highly Cited
2003
Highly Cited
2003
We provide phenotypic and functional evidence of premonocytoid dendritic cells (DCs) and preplasmacytoid DCs in blood and of… (More)
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Highly Cited
2000
Highly Cited
2000
Murine dendritic cells (DCs) can be classified into at least 2 subsets, "myeloid-related" (CD11b(bright), CD8alpha(-)) and… (More)
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Highly Cited
2000
Highly Cited
2000
Both granulocyte-macrophage colony-stimulating factor (GM-CSF) and flt3-ligand (FL) induce the development of dendritic cells… (More)
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Highly Cited
1997
Highly Cited
1997
Daily treatment of mice with recombinant human Flt3 ligand (huFlt3L) results in a dramatic numerical increase in the number of… (More)
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1997
1997
The ligand for flt-3 (FLT3L) exhibits striking structural homology with stem cell factor (SCF) and monocyte colony-stimulating… (More)
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1996
1996
B cell development is influenced by interactions between B cell progenitors and stromal cells. The precise mechanisms by which… (More)
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1996
1996
Flt3 ligand (flt3L) is a member of a small family of cytokines acting as tyrosine kinase receptor ligands that stimulate the… (More)
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