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Recombinant Flt3 Ligand

Known as: Flt3-Ligand, FLT 3 Ligand, rhuFlt3L 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine Flt3. Flt3 ligand binds to the Flt3 tyrosine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2020
Highly Cited
2020
  • N. Vaninov
  • Nature Reviews Immunology
  • 2020
  • Corpus ID: 214798543
volume 20 | mAY 2020 | 277 Profiling of the innate immune cell types present in the KPC­ OG and KPL­ OG mouse models indicated… Expand
Highly Cited
2019
Highly Cited
2019
Indolent non-Hodgkin’s lymphomas (iNHLs) are incurable with standard therapy and are poorly responsive to checkpoint blockade… Expand
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Highly Cited
2016
Highly Cited
2016
Large numbers of melanoma lesions develop resistance to targeted inhibition of mutant BRAF or fail to respond to checkpoint… Expand
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Highly Cited
2008
Highly Cited
2008
The development of distinct dendritic cell (DC) subsets is regulated by cytokines. The ligand for the FMS-like tyrosine kinase 3… Expand
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Highly Cited
2006
Highly Cited
2006
Plasmacytoid dendritic cells (PDCs), which produce IFN-alpha in response to autoimmune complexes containing nuclear antigens, are… Expand
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Highly Cited
2005
Highly Cited
2005
In spite of preclinical efficacy and recent randomized, controlled studies with adenoviral vectors expressing herpes simplex… Expand
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Highly Cited
2003
Highly Cited
2003
The signals that control decisions of progenitor commitment involve the interplay of both cytokines and transcription factors… Expand
Highly Cited
2000
Highly Cited
2000
Both granulocyte-macrophage colony-stimulating factor (GM-CSF) and flt3-ligand (FL) induce the development of dendritic cells… Expand
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Highly Cited
1997
Highly Cited
1997
Daily treatment of mice with recombinant human Flt3 ligand (huFlt3L) results in a dramatic numerical increase in the number of… Expand
Highly Cited
1996
Highly Cited
1996
Flt3 ligand (flt3L) is a member of a small family of cytokines acting as tyrosine kinase receptor ligands that stimulate the… Expand
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