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Recombinant Fibroblast Growth Factor 1

Known as: aFGF, FGF-1, Heparin Binding Growth Factor 
A recombinant therapeutic agent which is chemically identical to or similar to endogenous fibroblast growth factor 1 (FGF-1. Because of the mitogenic… 
National Institutes of Health

Related topics

Related topics

5 relations
FGF1 geneFGF1 wt AlleleFibroblast Growth Factor 1, humanHeparin Binding Growth Factor

Broader (1)

fibroblast growth factor-1

Papers overview

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Highly Cited
2013
Highly Cited
2013
Electrical Stimulation Promotes Wound Healing by Enhancing Dermal Fibroblast Activity and Promoting Myofibroblast Transdifferentiation
Electrical stimulation (ES) has long been used as an alternative clinical treatment and an effective approach to modulate… 
Highly Cited
2005
Highly Cited
2005
α-Tocopheryl Succinate Inhibits Malignant Mesothelioma by Disrupting the Fibroblast Growth Factor Autocrine Loop
We have studied the potential effect against human malignant mesotheliomas (MM) of α-tocopheryl succinate (α-TOS), a redox-silent… 
Highly Cited
2004
Highly Cited
2004
Design of fully active FGF-1 variants with increased stability.
Fibroblast growth factor 1 is a powerful mitogen playing an important role in morphogenesis, angiogenesis and wound healing and… 
Highly Cited
2003
Highly Cited
2003
Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression
Summary Age is an important factor in the development and spread of breast cancer. Stromal cells also contribute to breast cancer… 
Highly Cited
2000
Highly Cited
2000
Fibroblast growth factors: an epigenetic mechanism of broad spectrum resistance to anticancer drugs.
Based on the observation that removal of tumors from metastatic organs reversed their chemoresistance, we hypothesized that… 
Highly Cited
1999
Highly Cited
1999
Acidic fibroblast growth factor induces an antifibrogenic phenotype in human lung fibroblasts.
Acidic fibroblast growth factor (FGF-1), a prototype member of the heparin-binding growth factor family, influences proliferation… 
Highly Cited
1997
Highly Cited
1997
Transfection with aFGF cDNA improves wound healing.
Somatic gene therapy is a potentially useful strategy for the delivery of growth factors or cytokines to enhance wound healing… 
Highly Cited
1995
Highly Cited
1995
Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells.
Wound repair and tumor vascularization depend upon blood vessel growth into hypoxic tissue. Although hypoxia slows endothelial… 
Highly Cited
1989
Highly Cited
1989
Growth of normal human keratinocytes and fibroblasts in serum‐free medium is stimulated by acidic and basic fibroblast growth factor
Keratinocytes and fibroblasts isolated from human neonatal foreskin can be plated and grown through multiple rounds of division… 
Review
1987
Review
1987
Structural characterization and biological functions of fibroblast growth factor.
I. Introduction BASIC AND acidic fibroblast growth factors (FGFs) are closely related molecules that show a similar range of… 
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