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Receptors, Purinergic P2X

Known as: P2X Purinoceptor, Purinoceptors, P2X, Purinoceptor, P2X 
A subclass of purinergic P2 receptors that signal by means of a ligand-gated ion channel. They are comprised of three P2X subunits which can be… Expand
National Institutes of Health

Papers overview

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Review
2006
Review
2006
Significant progress in understanding the pharmacological characteristics and physiological importance of homomeric and… Expand
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Review
2002
Review
2002
Activation of purinoceptors by extracellular ATP is an important component of the glial response to injury in the central nervous… Expand
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Highly Cited
2000
Highly Cited
2000
1 Using functional co‐cultures of rat carotid body (CB) O2 chemoreceptors and ‘juxtaposed’ petrosal neurones (JPNs), we tested… Expand
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Highly Cited
1997
Highly Cited
1997
The classification of receptors for adenosine, ATP and ADP (collectively called purinoceptors) has seen a number of developments… Expand
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Highly Cited
1995
Highly Cited
1995
ATP is known to depolarize sensory neurons, and may play a role in nociceptor activation when released from damaged tissue1-10… Expand
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Highly Cited
1995
Highly Cited
1995
cDNAs encoding P2x purinoceptors from human bladder smooth muscle and from rat PC-12 cells were expressed in oocytes and human… Expand
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Highly Cited
1995
Highly Cited
1995
We have cloned P2X4, a member of the P2‐purinoceptor family, which has a new pharmacological profile. Rat P2X4 is distantly… Expand
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Highly Cited
1995
Highly Cited
1995
1. Whole‐cell recordings were made from guinea‐pig coeliac, rat nodose and rat superior cervical (SCG) neurones in culture, and… Expand
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Review
1991
Review
1991
Characterization of P2-purinoceptor subtypes has facilitated understanding of the many diverse effects produced by purine… Expand
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Highly Cited
1990
Highly Cited
1990
1 Suramin, an inhibitor of several types of ATPase, was investigated for its ability to antagonize responses mediated via P2X… Expand
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