Receptor-Interacting Serine/Threonine Protein Kinase 2

Known as: RICK Protein, Receptor Interacting Serine Threonine Kinase 2, CARDIAK 
A RIP serine-theonine kinase that contains a C-terminal caspase activation and recruitment domain. It can signal by associating with other CARD… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2014
01219982014

Papers overview

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2014
2014
Novel drugs are designed against specific molecular targets, but almost unavoidably they bind non-targets, which can cause… (More)
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2009
2009
The transcription factor NF-κB (nuclear factor κB) is a central mediator of inflammatory and apoptotic signaling in the cell. The… (More)
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2009
2009
RIP2/RICK/CARDIAK is a member of the receptor interacting protein kinase (RIP) family. RIP2 promotes NF-kappaB activation as well… (More)
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Review
2008
Review
2008
Biological markers of disease have become increasingly important for the clinician to diagnose, predict and monitor progression… (More)
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2007
2007
Although they are often portrayed as simple linear pathways that connect receptors to gene expression, tyrosine kinase–dependent… (More)
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Highly Cited
2002
Highly Cited
2002
The immune system consists of two evolutionarily different but closely related responses, innate immunity and adaptive immunity… (More)
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Highly Cited
2002
Highly Cited
2002
Host defences to microorganisms rely on a coordinated interplay between the innate and adaptive responses of immunity. Infection… (More)
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2001
2001
Not all caspases are as focused on apoptosis as some of us are. In fact, the first identified caspase (before there were… (More)
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1999
1999
Several lines of evidence suggest that host genetic factors controlling the immune response influence infection by Mycobacterium… (More)
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Highly Cited
1998
Highly Cited
1998
Members of the tumor necrosis factor receptor (TNFR) superfamily have an important role in the induction of cellular signals… (More)
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