Receptor Desensitization

Known as: Desensitization 
A multicellular process that regulates the extent of response to a stimulus either by modulation of active receptors or inhibition of intracellular… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Ionotropic glutamate receptors mediate most excitatory neurotransmission in the central nervous system and function by opening a… (More)
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Review
2004
Review
2004
Proteases acting at the surface of cells generate and destroy receptor agonists and activate and inactivate receptors, thereby… (More)
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Highly Cited
2002
Highly Cited
2002
Ligand-gated ion channels transduce chemical signals into electrical impulses by opening a transmembrane pore in response to… (More)
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Highly Cited
2002
Highly Cited
2002
The capsaicin receptor, VR1 (also known as TRPV1), is a ligand-gated ion channel expressed on nociceptive sensory neurons that… (More)
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Review
2001
Review
2001
Proteinase-activated receptors are a recently described, novel family of seven-transmembrane G-protein-coupled receptors. Rather… (More)
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Highly Cited
2000
Highly Cited
2000
Morphine is a powerful pain reliever, but also a potent inducer of tolerance and dependence. The development of opiate tolerance… (More)
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Highly Cited
1997
Highly Cited
1997
Tobacco use in developed countries is estimated to be the single largest cause of premature death. Nicotine is the primary… (More)
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Review
1996
Review
1996
The role of desensitization of ligand-gated channels at fast chemical synapses has been difficult to establish. Densensitization… (More)
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Highly Cited
1995
Highly Cited
1995
We studied the role of desensitization at inhibitory synapses by comparing nonequilibrium GABAA channel gating with inhibitory… (More)
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Highly Cited
1993
Highly Cited
1993
We have investigated the role of AMPA receptor desensitization during transmission at a calyceal synapse. Cyclothiazide blocked… (More)
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