Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Ras Protein Specific Guanine Nucleotide Releasing Factor 1

Known as: ras Guanine Nucleotide Releasing Factor, GNRP, CDC25 
The protein is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
The CDC25 phosphatases are key regulators of normal cell division and the cell's response to DNA damage. Earlier studies… Expand
Highly Cited
2003
Highly Cited
2003
The NMDA subtype of glutamate receptors (NMDAR) at excitatory neuronal synapses plays a key role in synaptic plasticity. The… Expand
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Highly Cited
2000
Highly Cited
2000
A checkpoint operating in the G2 phase of the cell cycle prevents entry into mitosis in the presence of DNA damage. UCN-01, a… Expand
Highly Cited
1998
Highly Cited
1998
The cis/trans peptidyl‐prolyl isomerase, Pin1, is a regulator of mitosis that is well conserved from yeast to man. Here we… Expand
Highly Cited
1998
Highly Cited
1998
Phosphatidylinositol 3‐kinase (PI3K) mediates a variety of cellular responses by generating PtdIns(3,4)P2 and PtdIns(3,4,5)P3… Expand
Highly Cited
1998
Highly Cited
1998
Guanine nucleotide exchange factors (GEFs) activate Ras proteins by stimulating the exchange of GTP for GDP in a multistep… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • table 2
Highly Cited
1996
Highly Cited
1996
Cdc2, the cyclin-dependent kinase that controls mitosis, is negatively regulated by phosphorylation on its threonine-14 and… Expand
Highly Cited
1993
Highly Cited
1993
A human complementary DNA was isolated that encodes a widely expressed protein, hSos1, that is closely related to Sos, the… Expand
Highly Cited
1993
Highly Cited
1993
To contribute to a deeper understanding of M-phase control in eukaryotic cells, we have constructed a model based on the… Expand
  • figure 1
  • figure 3
  • table 1
  • figure 4
  • figure 5
Highly Cited
1987
Highly Cited
1987
The gene corresponding to the S. cerevisiae cell division cycle mutant cdc25 has been cloned and sequenced, revealing an open… Expand
  • table 1
  • figure 1
  • table 2
  • figure 3
  • table 3