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Ras Protein Specific Guanine Nucleotide Releasing Factor 1
Known as:
ras Guanine Nucleotide Releasing Factor
, GNRP
, CDC25
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The protein is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has…
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National Institutes of Health
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Related topics
Related topics
18 relations
CDC25 and CHK1 Regulatory Pathway
G2-M Cell Cycle Checkpoint
In Blood
Memory
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CDC25 protein, S cerevisiae
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
The when and wheres of CDC25 phosphatases.
R. Boutros
,
C. Dozier
,
B. Ducommun
Current opinion in cell biology
2006
Corpus ID: 19684250
Highly Cited
2003
Highly Cited
2003
The NMDA Receptor Is Coupled to the ERK Pathway by a Direct Interaction between NR2B and RasGRF1
G. Krapivinsky
,
L. Krapivinsky
,
+6 authors
I. Medina
Neuron
2003
Corpus ID: 10090520
Highly Cited
2001
Highly Cited
2001
Pin1 acts catalytically to promote a conformational change in Cdc25.
P. Stukenberg
,
M. Kirschner
Molecular cell
2001
Corpus ID: 27459655
Highly Cited
2000
Highly Cited
2000
The Chk1 Protein Kinase and the Cdc25C Regulatory Pathways Are Targets of the Anticancer Agent UCN-01*
P. Graves
,
Lijia Yu
,
+4 authors
H. Piwnica-Worms
The Journal of Biological Chemistry
2000
Corpus ID: 6029262
A checkpoint operating in the G2 phase of the cell cycle prevents entry into mitosis in the presence of DNA damage. UCN-01, a…
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Highly Cited
1998
Highly Cited
1998
The mitotic peptidyl‐prolyl isomerase, Pin1, interacts with Cdc25 and Plx1
D. G. Crenshaw
,
J. Yang
,
A. Means
,
S. Kornbluth
The EMBO journal
1998
Corpus ID: 19909407
The cis/trans peptidyl‐prolyl isomerase, Pin1, is a regulator of mitosis that is well conserved from yeast to man. Here we…
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Highly Cited
1996
Highly Cited
1996
Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts
A. Kumagai
,
W. Dunphy
Science
1996
Corpus ID: 1625414
Cdc2, the cyclin-dependent kinase that controls mitosis, is negatively regulated by phosphorylation on its threonine-14 and…
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Highly Cited
1996
Highly Cited
1996
Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS–M
C. Plass
,
H. Shibata
,
+10 authors
V. Chapman
Nature Genetics
1996
Corpus ID: 47562253
Normal mammalian development requires a diploid combination of both haploid parental genomes1. Uniparental disomy for certain…
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Highly Cited
1993
Highly Cited
1993
Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.
P. Chardin
,
J. Camonis
,
+4 authors
D. Bar-Sagi
Science
1993
Corpus ID: 11997087
A human complementary DNA was isolated that encodes a widely expressed protein, hSos1, that is closely related to Sos, the…
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Highly Cited
1993
Highly Cited
1993
Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos.
B. Novák
,
J. Tyson
Journal of cell science
1993
Corpus ID: 14116987
To contribute to a deeper understanding of M-phase control in eukaryotic cells, we have constructed a model based on the…
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Highly Cited
1987
Highly Cited
1987
The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway
D. Broek
,
T. Toda
,
+5 authors
M. Wigler
Cell
1987
Corpus ID: 37944501
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