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Ran guanyl-nucleotide exchange factor activity

Known as: RCC1 
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ran family. Under normal cellular physiological conditions, the… Expand
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
The small GTPase Ran enzyme regulates critical eukaryotic cellular functions including nuclear transport and mitosis through the… Expand
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Highly Cited
2004
Highly Cited
2004
Spindle assembly is subject to the regulatory controls of both the cell-cycle machinery and the Ran-signaling pathway. An… Expand
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Highly Cited
2001
Highly Cited
2001
The Ran guanosine triphosphatase (GTPase) controls nucleocytoplasmic transport, mitotic spindle formation, and nuclear envelope… Expand
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Highly Cited
1996
Highly Cited
1996
The gene for retinitis pigmentosa 3 (RP3), the most frequent form of X-linked RP (XLRP), has been mapped previously to a… Expand
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Highly Cited
1995
Highly Cited
1995
The interaction of Ran, a Ras-related nuclear GTP-binding protein, with its guanine nucleotide exchange factor RCC1 has been… Expand
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Highly Cited
1995
Highly Cited
1995
RCC1 (the regulator of chromosome condensation) stimulates guanine nucleotide dissociation on the Ras-related nuclear protein Ran… Expand
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Highly Cited
1995
Highly Cited
1995
The guanine nucleotide dissociation and GTPase reactions of Ran, a Ras-related nuclear protein, have been investigated using… Expand
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Highly Cited
1991
Highly Cited
1991
THE product of the gene RCC1 (regulator of chromosome condensation) in a BHK cell line is involved in the control of mitotic… Expand
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Highly Cited
1991
Highly Cited
1991
The temperature-sensitive mutant cell line tsBN2, was derived from the BHK21 cell line and has a point mutation in the RCC1 gene… Expand
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Highly Cited
1989
Highly Cited
1989
The RCC1 gene, a regulator for the onset of chromosome condensation was found to encode a protein with a molecular mass of 45 kD… Expand
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