Raloxifene Hydrochloride

Known as: Raloxifene Hydrochloride [Chemical/Ingredient], (6-Hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone Hydrochloride, Raloxifene HCl 
The hydrochloride salt form of raloxifene, a selective benzothiophene estrogen receptor modulator (SERM) with lipid lowering effects and activity… (More)

Topic mentions per year

Topic mentions per year

1987-2017
010020019872017

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Tamoxifen and raloxifene have limited patient acceptance for primary prevention of breast cancer. Aromatase inhibitors… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT Tamoxifen is approved for the reduction of breast cancer risk, and raloxifene has demonstrated a reduced risk of breast… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The effect of raloxifene, a selective estrogen-receptor modulator, on coronary heart disease (CHD) and breast cancer… (More)
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Highly Cited
2005
Highly Cited
2005
phene that binds ta estrogen receptars and inhibits bone resorption without stimulating the uterine endametrium in pastmenapausal… (More)
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Highly Cited
2002
Highly Cited
2002
Selective estrogen receptor modulators (SERMs) mimic estrogen action in certain tissues while opposing it in others. The… (More)
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Highly Cited
1999
Highly Cited
1999
CONTEXT Raloxifene hydrochloride, a selective estrogen receptor modulator, prevents bone loss in postmenopausal women, but… (More)
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Highly Cited
1998
Highly Cited
1998
CONTEXT Raloxifene is a selective estrogen receptor modulator that has estrogen-agonistic effects on bone and estrogen… (More)
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Highly Cited
1997
Highly Cited
1997
The transactivation properties of the two estrogen receptors, ERalpha and ERbeta, were examined with different ligands in the… (More)
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Highly Cited
1997
Highly Cited
1997
Oestrogens are involved in the growth, development and homeostasis of a number of tissues. The physiological effects of these… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Long-term estrogen therapy can reduce the risk of osteoporotic fracture and cardiovascular disease in postmenopausal… (More)
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