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Rad51 Recombinase
Known as:
RAD51 Protein
, Rad51 Recombinase [Chemical/Ingredient]
, Recombinase, Rad51
A Rec A recombinase found in eukaryotes. Rad51 is involved in DNA REPAIR of double-strand breaks.
National Institutes of Health
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8 relations
In Blood
Process of secretion
RAD51 gene
antagonists & inhibitors
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Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Jingfei Xu
,
Lingyun Zhao
,
Yuanyuan Xu
,
Weixing Zhao
,
P. Sung
,
Hongwei Wang
Nature Structural &Molecular Biology
2017
Corpus ID: 11477783
The central step in eukaryotic homologous recombination (HR) is ATP-dependent DNA-strand exchange mediated by the Rad51…
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2016
2016
Tyrosine phosphorylation stimulates activity of human RAD51 recombinase through altered nucleoprotein filament dynamics
S. Subramanyam
,
Mohammed Ismail
,
Ipshita Bhattacharya
,
M. Spies
Proceedings of the National Academy of Sciences
2016
Corpus ID: 54320
Significance Homologous recombination provides the most accurate means to repair genotoxic DNA lesions. It depends on the…
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2007
2007
Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica
Mavil López-Casamichana
,
E. Orozco
,
L. Marchat
,
C. López-Camarillo
BMC Molecular Biology
2007
Corpus ID: 1053153
BackgroundIn eukaryotic and prokaryotic cells, homologous recombination is an accurate mechanism to generate genetic diversity…
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Highly Cited
2006
Highly Cited
2006
Roles of ATP binding and ATP hydrolysis in human Rad51 recombinase function.
Peter Chi
,
S. van Komen
,
Michael G. Sehorn
,
S. Sigurdsson
,
P. Sung
DNA repair
2006
Corpus ID: 44507025
Highly Cited
2004
Highly Cited
2004
Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange
Michael G. Sehorn
,
S. Sigurdsson
,
W. Bussen
,
V. Unger
,
P. Sung
Nature
2004
Corpus ID: 4316803
Homologous recombination is crucial for the repair of DNA breaks and maintenance of genome stability. In Escherichia coli…
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Highly Cited
2004
Highly Cited
2004
Conformational changes modulate the activity of human RAD51 protein.
Yilun Liu
,
A. Stasiak
,
J. Masson
,
M. McIlwraith
,
A. Stasiak
,
S. West
Journal of molecular biology
2004
Corpus ID: 35867287
Highly Cited
2002
Highly Cited
2002
Structure of the single-strand annealing domain of human RAD52 protein
M. Singleton
,
L. M. Wentzell
,
Yilun Liu
,
S. West
,
D. Wigley
Proceedings of the National Academy of Sciences…
2002
Corpus ID: 3035101
In eukaryotic cells, RAD52 protein plays a central role in genetic recombination and DNA repair by (i) promoting the annealing of…
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Highly Cited
1997
Highly Cited
1997
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase.
P. Sung
Genes & development
1997
Corpus ID: 42929556
Saccharomyces cerevisiae RAD51, RAD55, and RAD57 genes, required for genetic recombination and DNA double-strand-break repair…
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Highly Cited
1996
Highly Cited
1996
Yeast Rad51 Recombinase Mediates Polar DNA Strand Exchange in the Absence of ATP Hydrolysis*
P. Sung
,
S. Stratton
The Journal of Biological Chemistry
1996
Corpus ID: 8364953
Saccharomyces cerevisiae RAD51 gene is required for genetic recombination and recombinational repair of DNA strand breaks. Rad51…
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Highly Cited
1994
Highly Cited
1994
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein.
P. Sung
Science
1994
Corpus ID: 23615292
The RAD51 gene of Saccharomyces cerevisiae is required for genetic recombination and DNA double-strand break repair. Here it is…
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