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The central step in eukaryotic homologous recombination (HR) is ATP-dependent DNA-strand exchange mediated by the Rad51… Expand Significance Homologous recombination provides the most accurate means to repair genotoxic DNA lesions. It depends on the… Expand BackgroundIn eukaryotic and prokaryotic cells, homologous recombination is an accurate mechanism to generate genetic diversity… Expand The Rad51 recombinase polymerizes on ssDNA to yield a right-handed nucleoprotein filament, called the presynaptic filament, that… Expand Homologous recombination is crucial for the repair of DNA breaks and maintenance of genome stability. In Escherichia coli… Expand Homologous recombination provides a major pathway for the repair of DNA double-strand breaks in mammalian cells. Defects in… Expand In eukaryotic cells, RAD52 protein plays a central role in genetic recombination and DNA repair by (i) promoting the annealing of… Expand Saccharomyces cerevisiae RAD51, RAD55, and RAD57 genes, required for genetic recombination and DNA double-strand-break repair… Expand Saccharomyces cerevisiae RAD51 gene is required for genetic recombination and recombinational repair of DNA strand breaks. Rad51… Expand The RAD51 gene of Saccharomyces cerevisiae is required for genetic recombination and DNA double-strand break repair. Here it is… Expand