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RX-5902
Known as:
P-p68 Inhibitor RX-5902
An orally bioavailable small molecule inhibitor of phosphorylated-p68 RNA helicase (P-p68), with potential anti-proliferative and antineoplastic…
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National Institutes of Health
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Related topics
Related topics
3 relations
NCIt Antineoplastic Agent Terminology
Broader (2)
Piperazines
Quinoxalines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract P5-21-16: Preclinical studies of RX-5902, a beta-catenin modulator in triple negative breast cancer
J. Tentler
,
J. Frank
,
+10 authors
J. Diamond
2018
Corpus ID: 56693270
Background: RX-5902 (Supinoxin) is a novel anti-cancer compound that targets phosphorylated p68 RNA helicase, a member of the…
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2016
2016
Abstract P5-03-13: The anticancer effects of Supinoxin® (RX-5902) in triple-negative breast cancer MDA-MB-231 through phosphorylated p68 on Tyr593
Deog Joong Kim
,
M. Yang
,
Y. Lee
,
J. Reményi
,
F. Fuller-Pace
2016
Corpus ID: 57080831
Several studies have indicated that the DEAD box RNA helicase DDX5/p68 plays several important roles in cancer (1, 2). In…
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2016
2016
Phase 1/2a study of RX-5902 in advanced solid tumors (ST): An orally bioavailable inhibitor of phosphorylated P68 and modulator of β-catenin nuclear translocation
S. Eckhardt
,
W. L. Gluck
,
M. Gutierrez
,
C. Peterson
,
R. Mazhari
,
E. Benaim
2016
Corpus ID: 79311173
Modulator of β-Catenin Nuclear Translocation S. Gail Eckhardt1 , W. Larry Gluck2, Martin Gutierrez3, Christine Peterson4, Reza…
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2015
2015
Interferes with β-Catenin Function through Y 593 phospho-p 68 RNA Helicase †
Gina Chun Kost
,
M. Yang
,
+6 authors
Zhiren Liu
2015
Corpus ID: 207762307