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RWJ 54428

Known as: RWJ-54428 
 

Topic mentions per year

Topic mentions per year

1999-2008
01219992008

Related topics

Related topics

2 relations

Broader (1)

Cephalosporins

Narrower (1)

MC-02,479

Related mentions per year

Related mentions per year

1951-2018
1960198020002020
RWJ 54428
Cephalosporins
MC-02,479

Papers overview

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Review
2009
Review
2009
Beta-lactams and beta-lactamase-inhibitors in current- or potential-clinical practice: a comprehensive update.
The use of successive generations of beta-lactams has selected successive generations of beta-lactamases including CTX-M ESBLs… (More)
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2008
2008
Pharmacodynamics of RWJ-54428 against Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis in a neutropenic mouse thigh infection model.
RWJ-54428 (also known as MC-02,479) is a new cephalosporin with promising activity against gram-positive bacteria. The… (More)
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2003
2003
In vivo antibacterial activity of RWJ-54428, a new cephalosporin with activity against gram-positive bacteria.
RWJ-54428 (MC-02,479) is a new cephalosporin with activity against resistant gram-positive organisms, including methicillin… (More)
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2003
2003
RWJ-54428 (MC-02,479), a new cephalosporin with high affinity for penicillin-binding proteins, including PBP 2a, and stability to staphylococcal beta-lactamases.
RWJ-54428 (MC-02,479) is a new cephalosporin active against gram-positive bacteria, including methicillin-resistant… (More)
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2002
2002
In vitro activity of cephalosporin RWJ-54428 (MC-02479) against multidrug-resistant gram-positive cocci.
RWJ-54428 (MC-02479) is a novel cephalosporin that binds to penicillin-binding protein (PBP) PBP 2' (PBP 2a) of methicillin… (More)
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2002
2002
In vitro activity of a new cephalosporin, RWJ-54428, against streptococci, enterococci and staphylococci, including glycopeptide-intermediate Staphylococcus aureus.
The need for new antimicrobial agents with activity against Gram-positive organisms has become increasingly important because of… (More)
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Review
2001
Review
2001
In vitro activities of RWJ-54428 (MC-02,479) against multiresistant gram-positive bacteria.
RWJ-54428 (MC-02,479) is a new cephalosporin with a high level of activity against gram-positive bacteria. In a broth… (More)
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2000
2000
Discovery of RWJ-54428 (MC-02,479), a new cephalosporin active against resistant gram-positive bacteria.
The discovery of RWJ-54428 (MC-02,479), a new cephalosporin displaying promising activity against sensitive and resistant Gram… (More)
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2000
2000
SAR studies of anti-MRSA non-zwitterionic 3-heteroarylthiocephems.
SAR studies in a series of 3-heteroarylthio substituted cephalosporins established that high activity against methicillin… (More)
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Review
1999
Review
1999
Antibiotic resistance versus small molecules, the chemical evolution.
Two discovery approaches directed to addressing the problem of increasing bacterial resistance are described. The first is a… (More)
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