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RWJ 54428
Known as:
RWJ-54428
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Cephalosporins
Narrower (1)
MC-02,479
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Beta-lactams and Beta-lactamase-inhibitors in current- or potential-clinical practice: A comprehensive update
M. Shahid
,
F. Sobia
,
+4 authors
P. Hawkey
Critical reviews in microbiology
2009
Corpus ID: 5124776
The use of successive generations of β-lactams has selected successive generations of β-lactamases including CTX-M ESBLs, AmpC…
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2008
2008
Pharmacodynamics of RWJ-54428 against Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis in a Neutropenic Mouse Thigh Infection Model
D. C. Griffith
,
David Rodriguez
,
Erik Corcoran
,
M. Dudley
Antimicrobial Agents and Chemotherapy
2008
Corpus ID: 23460228
ABSTRACT RWJ-54428 (also known as MC-02,479) is a new cephalosporin with promising activity against gram-positive bacteria. The…
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Review
2005
Review
2005
Investigational new drugs for the treatment of resistant pneumococcal infections
H. Hoffman-Roberts
,
Emily C Babcock
,
Isaac F. Mitropoulos
Expert opinion on investigational drugs
2005
Corpus ID: 33507329
Antibiotic resistance in Streptococcus pneumoniae is not only increasing with penicillin but also with other antimicrobial…
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2003
2003
In Vivo Antibacterial Activity of RWJ-54428, a New Cephalosporin with Activity against Gram-Positive Bacteria
D. C. Griffith
,
L. Harford
,
Robert Williams
,
V. Lee
,
M. Dudley
Antimicrobial Agents and Chemotherapy
2003
Corpus ID: 20338456
ABSTRACT RWJ-54428 (MC-02,479) is a new cephalosporin with activity against resistant gram-positive organisms, including…
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2003
2003
RWJ-54428 (MC-02,479), a New Cephalosporin with High Affinity for Penicillin-Binding Proteins, Including PBP 2a, and Stability to Staphylococcal Beta-Lactamases
F. Malouin
,
J. Blais
,
+9 authors
M. Dudley
Antimicrobial Agents and Chemotherapy
2003
Corpus ID: 35207111
ABSTRACT RWJ-54428 (MC-02,479) is a new cephalosporin active against gram-positive bacteria, including methicillin-resistant…
Expand
2002
2002
In Vitro Activity of Cephalosporin RWJ-54428 (MC-02479) against Multidrug-Resistant Gram-Positive Cocci
Alan P. Johnson
,
M. Warner
,
M. Carter
,
D. Livermore
Antimicrobial Agents and Chemotherapy
2002
Corpus ID: 31019673
ABSTRACT RWJ-54428 (MC-02479) is a novel cephalosporin that binds to penicillin-binding protein (PBP) PBP 2′ (PBP 2a) of…
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2002
2002
In vitro activity of a new cephalosporin, RWJ-54428, against streptococci, enterococci and staphylococci, including glycopeptide-intermediate Staphylococcus aureus.
J. Swenson
,
F. Tenover
The Journal of antimicrobial chemotherapy
2002
Corpus ID: 26642271
The need for new antimicrobial agents with activity against Gram-positive organisms has become increasingly important because of…
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Review
2001
Review
2001
In Vitro Activities of RWJ-54428 (MC-02,479) against Multiresistant Gram-Positive Bacteria
S. Chamberland
,
J. Blais
,
+7 authors
M. Dudley
Antimicrobial Agents and Chemotherapy
2001
Corpus ID: 29363896
ABSTRACT RWJ-54428 (MC-02,479) is a new cephalosporin with a high level of activity against gram-positive bacteria. In a broth…
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2000
2000
Discovery of RWJ-54428 (MC-02,479), a new cephalosporin active against resistant gram-positive bacteria.
S. Hecker
,
T. Glinka
,
+5 authors
V. Lee
The Journal of antibiotics
2000
Corpus ID: 44575772
The discovery of RWJ-54428 (MC-02,479), a new cephalosporin displaying promising activity against sensitive and resistant Gram…
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Review
1999
Review
1999
Antibiotic resistance versus small molecules, the chemical evolution
V. Lee
,
S. Hecker
Medicinal research reviews
1999
Corpus ID: 31964462
Two discovery approaches directed to addressing the problem of increasing bacterial resistance are described. The first is a…
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