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RU 5135

Known as: 17-Azaandrost-16-en-11-one, 16-amino-3-hydroxy-, (3alpha,5beta)-, R 5135, RU-5135 
 
National Institutes of Health

Papers overview

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1996
1996
1 After 8 days in vitro, rat cerebellar granule cells were exposed to 1 mM γ‐aminobutyric acid (GABA) for periods of 1, 2, 4, 6… Expand
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1992
1992
The synthetic steroid amidine 3-alpha-hydroxy-16-imino-5-beta-17aza androstan-11-one (R 5135) is known to elicit long-lasting… Expand
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1992
1992
The alpha subunit of the glycine receptor purified from rat spinal cord is rapidly and specifically phosphorylated by protein… Expand
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Highly Cited
1991
Highly Cited
1991
An impermeant benzodiazepine receptor ligand was prepared by derivatization of the aminobenzodiazepine 1012‐S with 4… Expand
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1989
1989
Abstract: The thermodynamic parameters associated with the interactions of agonists and antagonists with glycine receptors in rat… Expand
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Highly Cited
1989
Highly Cited
1989
Cultures of cerebral neurons were prepared from chick embryos, 8.5 days in ovo, and maintained in vitro. Following chronic… Expand
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1985
1985
In the spinal cord of the pentobarbitone-anaesthetised cat, microelectrophoretic RU 5135, a steroid derivative, was a potent… Expand
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Highly Cited
1985
Highly Cited
1985
Acute injection of the gamma-aminobutyric acid (GABA) mimetics progabide, aminooxyacetic acid, gamma-acetylenic GABA and… Expand
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Highly Cited
1984
Highly Cited
1984
A series of tetrazole convulsants were examined for their potencies in displacing [35S]-t-butylbicyclophosphorothionate (TBPS… Expand
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Highly Cited
1981
Highly Cited
1981
A novel steroid derivative, R 5135 (3α-hydroxy-16-imino-5β-17-aza-androstan-11-one) showed high affinity for both the GABA and… Expand
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