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RSU 1069

Known as: RSU-1069 
 
National Institutes of Health

Papers overview

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Highly Cited
1990
Highly Cited
1990
alpha-[(1-Aziridinyl)methyl]-2-nitro-1H-imidazole-1-ethanols, of general formula ImCH2CH(OH)CH2NCR1R2CR3R4, where Im = 2… Expand
1989
1989
  • S. Cole, L. Robbins
  • Radiotherapy and oncology : journal of the…
  • 1989
  • Corpus ID: 4149519
The influence of altered tumour oxygenation on the responses to radiation and/or bioreductive 2-nitroimidazole compounds was… Expand
Highly Cited
1987
Highly Cited
1987
The effect of the vasodilator hydralazine on both the tumor and systemic toxicity of RSU-1069 has been evaluated in C57B1 mice… Expand
1987
1987
The interaction of the nitroimidazole-aziridines RSU-1069 and RSU-1131, as parent or radiation-reduced species, with plasmid DNA… Expand
Highly Cited
1986
Highly Cited
1986
A series of nitroimidazoles containing aziridine and alkyl-substituted aziridine functions has been synthesized. The 2… Expand
1986
1986
The radiosensitizing and cytotoxic properties of the drug RSU-1069, (1-(2-nitro-1-imidazolyl)-3-(1-aziridino)-2-propanol) a 2… Expand
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1986
1986
  • D. Chaplin
  • British Journal of Cancer
  • 1986
  • Corpus ID: 5904518
It is known that many solid animal tumours have a lower oxygenation level than most normal tissues and, in addition, that this… Expand
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1986
1986
RSU-1069 is the principal member of a new group of hypoxiccell radio- and chemo- (“mixed function”) sensitisers. They contain… Expand
1986
1986
RSU-1069 combines an aziridine function with a 2-nitroimidazole and has been reported to exhibit extraordinary radiosensitization… Expand
1986
1986
RSU 1069 is a substantially more efficient sensitizer than misonidazole when hypoxic Chinese hamster V79 cells are irradiated in… Expand