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RPR 117824
Known as:
RPR-117824
, RPR117824
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Imidazoles
Pyrazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Reduction of spastic tone increase after functional electrical stimulation in patients with spinal cord injury
P. Krause
,
J. Szécsi
,
A. Straube
Clinical Neurophysiology
2007
Corpus ID: 53173260
receptors at the single channel level, within synaptic contacts and networks in cell culture, and using brain slice techniques…
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2007
2007
Brains and projective functions
T. Kromer
Clinical Neurophysiology
2007
Corpus ID: 53192112
receptors at the single channel level, within synaptic contacts and networks in cell culture, and using brain slice techniques…
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2007
2007
Pharmacokinetic properties of selective and non-selective AMPA-receptor antagonists and their role in neuroprotection
F. Schlesinger
2007
Corpus ID: 8676660
In the study “Desensitization and resensitization are independently regulated in human recombinant GluR subunit coassemblies…
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2006
2006
Molecular analysis of the interaction of the pyrazine derivatives RPR119990 and RPR117824 with human AMPA-type glutamate receptor channels
K. Krampfl
,
F. Schlesinger
,
A. Cordes
,
J. Bufler
Neuropharmacology
2006
Corpus ID: 23071247
Antagonizing glutamatergic neurotransmission by blockade of AMPA-type glutamate receptors is a promising pharmacological strategy…
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Review
2004
Review
2004
Synthesis and structure-activity relationships of 4,10-dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazine derivatives: highly potent and selective AMPA receptor antagonists with in vivo activity.
J. Stutzmann
,
M. Vuilhorgne
,
S. Mignani
Mini reviews in medicinal chemistry
2004
Corpus ID: 20154575
The excitatory neurotransmitter glutamate interacts with ionotropic and metabotropic receptors that mediate a variety of normal…
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2002
2002
9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): selective anticonvulsive and neuroprotective AMPA antagonist.
S. Mignani
,
G. Bohme
,
+9 authors
J. M. Stutzmann
Bioorganic & medicinal chemistry
2002
Corpus ID: 23792373
Excessive release of glutamate, a potent excitatory neurotransmitter, is thought to play an important role in a variety of acute…
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