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RPA2 gene

Known as: Replication Protein A2, 32kDa Gene, RPA32, REPLICATION PROTEIN A2, 32-KD 
This gene is involved in DNA repair, recombination and replication.
National Institutes of Health

Related topics

Related topics

6 relations
DNA RepairDNA ReplicationRecombination, GeneticReplication Protein A 32 kDa Subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Causes Replication Catastrophe and Antitumor Effects through CHK 1-Dependent Mechanisms
CHK1 is a multifunctional protein kinase integral to both the cellular response to DNA damage and control of the number of active… 
Highly Cited
2011
Highly Cited
2011
Phosphorylation: The Molecular Switch of Double-Strand Break Repair
Repair of double-stranded breaks (DSBs) is vital to maintaining genomic stability. In mammalian cells, DSBs are resolved in one… 
2009
2009
An Alternative Form of Replication Protein A Prevents Viral Replication in Vitro*
Replication protein A (RPA), the eukaryotic single-stranded DNA-binding complex, is essential for multiple processes in cellular… 
2008
2008
DNA damage and homologous recombination signaling induced by thymidylate deprivation.
2006
2006
Differential involvement of phosphatidylinositol 3‐kinase‐related protein kinases in hyperphosphorylation of replication protein A2 in response to replication‐mediated DNA double‐strand breaks
Replication protein A2 (RPA2), a component of the RPA heterotrimer, is hyperphosphorylated and forms nuclear foci in response to… 
Highly Cited
2005
Highly Cited
2005
Modulation of Replication Protein A Function by Its Hyperphosphorylation-induced Conformational Change Involving DNA Binding Domain B*
Human replication protein A (RPA), composed of RPA70, RPA32, and RPA14 subunits, undergoes hyperphosphorylation in cells in… 
2003
2003
MEC1-dependent phosphorylation of yeast RPA1 in vitro.
Highly Cited
2002
Highly Cited
2002
Human tumor suppressor ARF impedes S-phase progression independent of p53.
Using alternative reading frames, the human ARF-INK4a locus encodes two unrelated proteins that both function in tumor… 
2001
2001
Inhibition of DNA replication by tirapazamine.
Tirapazamine (TPZ) is a hypoxia-selective cytotoxin that is currently being examined in Phase II and III clinical trials in… 
Highly Cited
1996
Highly Cited
1996
Phosphorylation of human replication protein A by the DNA-dependent protein kinase is involved in the modulation of DNA replication.
The single-stranded DNA-binding protein, Replication Protein A (RPA), is a heterotrimeric complex with subunits of 70, 32 and 14… 
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