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RPA2 gene

Known as: Replication Protein A2, 32kDa Gene, RPA32, REPLICATION PROTEIN A2, 32-KD 
This gene is involved in DNA repair, recombination and replication.
National Institutes of Health

Related topics

Related topics

6 relations
DNA RepairDNA ReplicationRecombination, GeneticReplication Protein A 32 kDa Subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
A Protein Array Screen for Kaposi's Sarcoma-Associated Herpesvirus LANA Interactors Links LANA to TIP60, PP2A Activity, and Telomere Shortening
ABSTRACT The Kaposi's sarcoma-associated herpesvirus (KSHV) LANA protein functions in latently infected cells as an essential… 
Highly Cited
2011
Highly Cited
2011
Phosphorylation: The Molecular Switch of Double-Strand Break Repair
Repair of double-stranded breaks (DSBs) is vital to maintaining genomic stability. In mammalian cells, DSBs are resolved in one… 
Highly Cited
2009
Highly Cited
2009
Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1.
Replication protein A (RPA) is a heterotrimeric protein consisting of RPA1, RPA2, and RPA3 subunits that binds to single-stranded… 
Highly Cited
2009
Highly Cited
2009
Proteomic analysis of multidrug‐resistance mechanisms in adriamycin‐resistant variants of DLKP, a squamous lung cancer cell line
Alterations in protein expression associated with adriamycin resistance in a panel of variants derived from the poorly… 
2009
2009
An Alternative Form of Replication Protein A Prevents Viral Replication in Vitro*
Replication protein A (RPA), the eukaryotic single-stranded DNA-binding complex, is essential for multiple processes in cellular… 
2006
2006
Differential involvement of phosphatidylinositol 3‐kinase‐related protein kinases in hyperphosphorylation of replication protein A2 in response to replication‐mediated DNA double‐strand breaks
Replication protein A2 (RPA2), a component of the RPA heterotrimer, is hyperphosphorylated and forms nuclear foci in response to… 
Highly Cited
2005
Highly Cited
2005
Modulation of Replication Protein A Function by Its Hyperphosphorylation-induced Conformational Change Involving DNA Binding Domain B*
Human replication protein A (RPA), composed of RPA70, RPA32, and RPA14 subunits, undergoes hyperphosphorylation in cells in… 
Highly Cited
2002
Highly Cited
2002
Human tumor suppressor ARF impedes S-phase progression independent of p53.
Using alternative reading frames, the human ARF-INK4a locus encodes two unrelated proteins that both function in tumor… 
Highly Cited
1997
Highly Cited
1997
Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function.
7-Hydroxystaurosporine (UCN-01) is a selective protein kinase C inhibitor in clinical trial for cancer treatment. In this study… 
Highly Cited
1996
Highly Cited
1996
Phosphorylation of human replication protein A by the DNA-dependent protein kinase is involved in the modulation of DNA replication.
The single-stranded DNA-binding protein, Replication Protein A (RPA), is a heterotrimeric complex with subunits of 70, 32 and 14… 
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